Publications for Anna Krook

Article

1 Sjogren RJO, Rizo-Roca D, Chibalin AV, Chorell E, Furrer R, Katayama S, Harada J, Karlsson HKR, Handschin C, Moritz T, Krook A, Naslund E, Zierath JR. Branched-chain amino acid metabolism is regulated by ERR alpha in primary human myotubes and is further impaired by glucose loading in type 2 diabetes. DIABETOLOGIA 2021 64:9 2077-2091
2 Gonzalez-Franquesa A, Stocks B, Borg ML, Kuefner M, Dalbram E, Nielsen TS, Agrawal A, Pankratova S, Chibalin AV, Karlsson HKR, Gheibi S, Björnholm M, Jørgensen NR, Clemmensen C, Hostrup M, Treebak JT, Krook A, Zierath JR, Deshmukh AS. Discovery of thymosin β4 as a human exerkine and growth factor. American journal of physiology. Cell physiology 2021 321:5 C770-C778
3 Massart J, Sjögren RJO, Egan B, Garde C, Lindgren M, Gu W, Ferreira DMS, Katayama M, Ruas JL, Barrès R, O'Gorman DJ, Zierath JR, Krook A. Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism. Nature communications 2021 12:1 5948-
4 Valladolid-Acebes I, Avall K, Recio-Lopez P, Moruzzi N, Bryzgalova G, Bjornholm M, Krook A, Alonso EF, Ericsson M, Landfors F, Nilsson SK, Berggren PO, Juntti-Berggren L. Lowering apolipoprotein CIII protects against high-fat diet-induced metabolic derangements. SCIENCE ADVANCES 2021 7:11
5 Karlsson HKR, Kasahara A, Ikeda M, Chibalin AV, Harada J, Rydén M, Krook A, Kato M, Kubota K, Zierath JR. Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study. Metabolism: clinical and experimental 2021 118: 154726-
6 Smith JAB, Savikj M, Sethi P, Platt S, Gabriel BM, Hawley JA, Dunstan D, Krook A, Zierath JR, Näslund E. Three weeks of interrupting sitting lowers fasting glucose and glycemic variability, but not glucose tolerance, in free-living women and men with obesity. American journal of physiology. Endocrinology and metabolism 2021 321:2 E203-E216
7 Batista TM, Jayavelu AK, Albrechtsen NJW, Iovino S, Lebastchi J, Pan H, Dreyfuss JM, Krook A, Zierath JR, Mann M, Kahn CR. A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes. CELL METABOLISM 2020 32:5 844-859.e5
8 Abdelmoez AM, Sardón Puig L, Smith JAB, Gabriel BM, Savikj M, Dollet L, Chibalin AV, Krook A, Zierath JR, Pillon NJ. Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism. American journal of physiology. Cell physiology 2020 318:3 C615-C626
9 Mancilla R, Krook A, Schrauwen P, Hesselink MKC. Diurnal Regulation of Peripheral Glucose Metabolism: Potential Effects of Exercise Timing. Obesity (Silver Spring, Md.) 2020 28 Suppl 1: S38-S45
10 Benrick A, Pillon NJ, Nilsson E, Lindgren E, Krook A, Ling C, Stener-Victorin E. Electroacupuncture Mimics Exercise-Induced Changes in Skeletal Muscle Gene Expression in Women With Polycystic Ovary Syndrome. The Journal of clinical endocrinology and metabolism 2020 105:6
11 Petrus P, Lecoutre S, Dollet L, Wiel C, Sulen A, Gao H, Tavira B, Laurencikiene J, Rooyackers O, Checa A, Douagi I, Wheelock CE, Arner P, McCarthy M, Bergo MO, Edgar L, Choudhury RP, Aouadi M, Krook A, Ryden M. Glutamine Links Obesity to Inflammation in Human White Adipose Tissue. CELL METABOLISM 2020 31:2 375-390.e11
12 Puig LS, Pillon NJ, Naslund E, Krook A, Zierath JR. Influence of obesity, weight loss, and free fatty acids on skeletal muscle clock gene expression. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 2020 318:1 E1-E10
13 Pillon NJ, Gabriel BM, Dollet L, Smith JAB, Sardón Puig L, Botella J, Bishop DJ, Krook A, Zierath JR. Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity. Nature communications 2020 11:1 470-
14 Savikj M, Gabriel BM, Alm PS, Smith J, Caidahl K, Björnholm M, Fritz T, Krook A, Zierath JR, Wallberg-Henriksson H. Afternoon exercise is more efficacious than morning exercise at improving blood glucose levels in individuals with type 2 diabetes: a randomised crossover trial. Diabetologia 2019 62:2 233-237
15 Lundström P, Caidahl K, Eriksson MJ, Fritz T, Krook A, Zierath JR, Rickenlund A. Changes in Vitamin D Status in Overweight Middle-Aged Adults with or without Impaired Glucose Metabolism in Two Consecutive Nordic Summers. Journal of nutrition and metabolism 2019 2019: 1840374-
16 Katayama M, Wiklander OPB, Fritz T, Caidahl K, El-Andaloussi S, Zierath JR, Krook A. Circulating Exosomal miR-20b-5p Is Elevated in Type 2 Diabetes and Could Impair Insulin Action in Human Skeletal Muscle. Diabetes 2019 68:3 515-526
17 Borg ML, Massart J, Schönke M, De Castro Barbosa T, Guo L, Wade M, Alsina-Fernandez J, Miles R, Ryan A, Bauer S, Coskun T, O'Farrell E, Niemeier EM, Chibalin AV, Krook A, Karlsson HK, Brozinick JT, Zierath JR. Modified UCN2 Peptide Acts as an Insulin Sensitizer in Skeletal Muscle of Obese Mice. Diabetes 2019 68:7 1403-1414
18 de Castro Barbosa T, Alm PS, Krook A, Barrès R, Zierath JR. Paternal high-fat diet transgenerationally impacts hepatic immunometabolism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 33:5 6269-6280
19 Lundell LS, Massart J, Altıntaş A, Krook A, Zierath JR. Regulation of glucose uptake and inflammation markers by FOXO1 and FOXO3 in skeletal muscle. Molecular metabolism 2019 20: 79-88
20 Aoi W, Hirano N, Lassiter DG, Bjornholm M, Chibalin AV, Sakuma K, Tanimura Y, Mizushima K, Takagi T, Naito Y, Zierath JR, Krook A. Secreted protein acidic and rich in cysteine (SPARC) improves glucose tolerance via AMP-activated protein kinase activation. FASEB JOURNAL 2019 33:9 10551-10562
21 Mashili FL, Ramaiya K, Lutale J, Njelekela M, Francis F, Zierath J, Krook A. Adiposity Is a Key Correlate of Circulating Fibroblast Growth Factor-21 Levels in African Males with or without Type 2 Diabetes Mellitus. Journal of obesity 2018 2018: 7461903-
22 Lassiter DG, Sjögren RJO, Gabriel BM, Krook A, Zierath JR. AMPK activation negatively regulates GDAP1, which influences metabolic processes and circadian gene expression in skeletal muscle. Molecular metabolism 2018 16: 12-23
23 Lassiter DG, Nylén C, Sjögren RJO, Chibalin AV, Wallberg-Henriksson H, Näslund E, Krook A, Zierath JR. FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle. Diabetologia 2018 61:2 424-432
24 Nylén C, Aoi W, Abdelmoez AM, Lassiter DG, Lundell LS, Wallberg-Henriksson H, Näslund E, Pillon NJ, Krook A. IL6 and LIF mRNA expression in skeletal muscle is regulated by AMPK and the transcription factors NFYC, ZBTB14, and SP1. American journal of physiology. Endocrinology and metabolism 2018 315:5 E995-E1004
25 Lundell LS, Savikj M, Kostovski E, Iversen PO, Zierath JR, Krook A, Chibalin AV, Widegren U. Protein translation, proteolysis and autophagy in human skeletal muscle atrophy after spinal cord injury. Acta physiologica (Oxford, England) 2018 223:3 e13051-
26 Savikj M, Ruby MA, Kostovski E, Iversen PO, Zierath JR, Krook A, Widegren U. Retained differentiation capacity of human skeletal muscle satellite cells from spinal cord-injured individuals. Physiological reports 2018 6:12 e13739-
27 Daskalaki E, Pillon NJ, Krook A, Wheelock CE, Checa A. The influence of culture media upon observed cell secretome metabolite profiles: The balance between cell viability and data interpretability. Analytica chimica acta 2018 1037: 338-350
28 Younis S, Schönke M, Massart J, Hjortebjerg R, Sundström E, Gustafson U, Björnholm M, Krook A, Frystyk J, Zierath JR, Andersson L. The ZBED6-IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals. Proceedings of the National Academy of Sciences of the United States of America 2018 115:9 E2048-E2057
29 Nilsson E, Benrick A, Kokosar M, Krook A, Lindgren E, Källman T, Martis MM, Højlund K, Ling C, Stener-Victorin E. Transcriptional and Epigenetic Changes Influencing Skeletal Muscle Metabolism in Women With Polycystic Ovary Syndrome. The Journal of clinical endocrinology and metabolism 2018 103:12 4465-4477
30 Massart J, Sjögren RJO, Lundell LS, Mudry JM, Franck N, O'Gorman DJ, Egan B, Zierath JR, Krook A. Altered miR-29 Expression in Type 2 Diabetes Influences Glucose and Lipid Metabolism in Skeletal Muscle. Diabetes 2017 66:7 1807-1818
31 Lund J, Rustan AC, Løvsletten NG, Mudry JM, Langleite TM, Feng YZ, Stensrud C, Brubak MG, Drevon CA, Birkeland KI, Kolnes KJ, Johansen EI, Tangen DS, Stadheim HK, Gulseth HL, Krook A, Kase ET, Jensen J, Thoresen GH. Exercise in vivo marks human myotubes in vitro: Training-induced increase in lipid metabolism. PloS one 2017 12:4 e0175441-
32 Alm PS, de Castro Barbosa T, Barrès R, Krook A, Zierath JR. Grandpaternal-induced transgenerational dietary reprogramming of the unfolded protein response in skeletal muscle. Molecular metabolism 2017 6:7 621-630
33 Pillon NJ, Krook A. Innate immune receptors in skeletal muscle metabolism. Experimental cell research 2017 360:1 47-54
34 Mudry JM, Lassiter DG, Nylén C, García-Calzón S, Näslund E, Krook A, Zierath JR. Insulin and Glucose Alter Death-Associated Protein Kinase 3 (DAPK3) DNA Methylation in Human Skeletal Muscle. Diabetes 2017 66:3 651-662
35 Kirchner H, Sinha I, Gao H, Ruby MA, Schönke M, Lindvall JM, Barrès R, Krook A, Näslund E, Dahlman-Wright K, Zierath JR. Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients. Molecular metabolism 2016 5:3 171-183
36 Mudry JM, Alm PS, Erhardt S, Goiny M, Fritz T, Caidahl K, Zierath JR, Krook A, Wallberg-Henriksson H. Direct effects of exercise on kynurenine metabolism in people with normal glucose tolerance or type 2 diabetes. Diabetes/metabolism research and reviews 2016 32:7 754-761
37 Lotta LA, Scott RA, Sharp SJ, Burgess S, Luan J, Tillin T, Schmidt AF, Imamura F, Stewart ID, Perry JR, Marney L, Koulman A, Karoly ED, Forouhi NG, Sjögren RJ, Näslund E, Zierath JR, Krook A, Savage DB, Griffin JL, Chaturvedi N, Hingorani AD, Khaw KT, Barroso I, McCarthy MI, O'Rahilly S, Wareham NJ, Langenberg C. Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis. PLoS medicine 2016 13:11 e1002179-
38 de Castro Barbosa T, Ingerslev LR, Alm PS, Versteyhe S, Massart J, Rasmussen M, Donkin I, Sjögren R, Mudry JM, Vetterli L, Gupta S, Krook A, Zierath JR, Barrès R. High-fat diet reprograms the epigenome of rat spermatozoa and transgenerationally affects metabolism of the offspring. Molecular metabolism 2016 5:3 184-197
39 Massart J, Katayama M, Krook A. microManaging glucose and lipid metabolism in skeletal muscle: Role of microRNAs. Biochimica et biophysica acta 2016 1861:12 Pt B 2130-2138
40 Osler ME, Fritz T, Caidahl K, Krook A, Zierath JR, Wallberg-Henriksson H. Changes in gene expression in responders and nonresponders to a low-intensity walking intervention. Diabetes care 2015 38:6 1154-60
41 Lane SC, Camera DM, Lassiter DG, Areta JL, Bird SR, Yeo WK, Jeacocke NA, Krook A, Zierath JR, Burke LM, Hawley JA. Effects of sleeping with reduced carbohydrate availability on acute training responses. Journal of applied physiology (Bethesda, Md. : 1985) 2015 119:6 643-55
42 Nascimento EB, Riedl I, Jiang LQ, Kulkarni SS, Näslund E, Krook A. Enhanced glucose metabolism in cultured human skeletal muscle after Roux-en-Y gastric bypass surgery. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2015 11:3 592-601
43 Ring M, Eriksson MJ, Fritz T, Nyberg G, Östenson CG, Krook A, Zierath JR, Caidahl K. Influence of physical activity and gender on arterial function in type 2 diabetes, normal and impaired glucose tolerance. Diabetes & vascular disease research 2015 12:5 315-24
44 Katayama M, Sjögren RJ, Egan B, Krook A. miRNA let-7 expression is regulated by glucose and TNF-α by a remote upstream promoter. The Biochemical journal 2015 472:2 147-56
45 Sjögren RJ, Egan B, Katayama M, Zierath JR, Krook A. Temporal analysis of reciprocal miRNA-mRNA expression patterns predicts regulatory networks during differentiation in human skeletal muscle cells. Physiological genomics 2015 47:3 45-57
46 Mudry JM, Massart J, Szekeres FL, Krook A. TWIST1 and TWIST2 regulate glycogen storage and inflammatory genes in skeletal muscle. The Journal of endocrinology 2015 224:3 303-13
47 Kirchner H, Nylen C, Laber S, Barrès R, Yan J, Krook A, Zierath JR, Näslund E. Altered promoter methylation of PDK4, IL1 B, IL6, and TNF after Roux-en Y gastric bypass. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2014 10:4 671-8
48 Agudelo LZ, Femenía T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson AT, Ferreira DMS, Krook A, Barres R, Zierath JR, Erhardt S, Lindskog M, Ruas JL. Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell 2014 159:1 33-45
49 Kostovski E, Boon H, Hjeltnes N, Lundell LS, Ahlsen M, Chibalin AV, Krook A, Iversen PO, Widegren U. Altered content of AMP-activated protein kinase isoforms in skeletal muscle from spinal cord injured subjects. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 2013 305:9 E1071-80
50 Jiang LQ, Duque-Guimaraes DE, Machado UF, Zierath JR, Krook A. Altered response of skeletal muscle to IL-6 in type 2 diabetic patients. Diabetes 2013 62:2 355-61
51 Tratsiakovich Y, Gonon AT, Krook A, Yang J, Shemyakin A, Sjöquist PO, Pernow J. Arginase inhibition reduces infarct size via nitric oxide, protein kinase C epsilon and mitochondrial ATP-dependent K+ channels. European journal of pharmacology 2013 712:1-3 16-21
52 Jiang LQ, Franck N, Egan B, Sjögren RJ, Katayama M, Duque-Guimaraes D, Arner P, Zierath JR, Krook A. Autocrine role of interleukin-13 on skeletal muscle glucose metabolism in type 2 diabetic patients involves microRNA let-7. American journal of physiology. Endocrinology and metabolism 2013 305:11 E1359-66
53 Staiger H, Bohm A, Scheler M, Berti L, Machann J, Schick F, Machicao F, Fritsche A, Stefan N, Weigert C, Krook A, Haring HU, de Angelis MH. Common Genetic Variation in the Human FNDC5 Locus, Encoding the Novel Muscle-Derived 'Browning' Factor Irisin, Determines Insulin Sensitivity. PLOS ONE 2013 8:4 e61903-
54 Mashili F, Chibalin AV, Krook A, Zierath JR. Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes. Diabetes 2013 62:2 457-65
55 Fritz T, Caidahl K, Krook A, Lundström P, Mashili F, Osler M, Szekeres FL, Östenson CG, Wändell P, Zierath JR. Effects of Nordic walking on cardiovascular risk factors in overweight individuals with type 2 diabetes, impaired or normal glucose tolerance. Diabetes/metabolism research and reviews 2013 29:1 25-32
56 Barres R, Kirchner H, Rasmussen M, Yan J, Kantor FR, Krook A, Näslund E, Zierath JR. Weight loss after gastric bypass surgery in human obesity remodels promoter methylation. Cell reports 2013 3:4 1020-7
57 Barres R, Yan J, Egan B, Treebak JT, Rasmussen M, Fritz T, Caidahl K, Krook A, O'Gorman DJ, Zierath JR. Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle. CELL METABOLISM 2012 15:3 405-11
58 Kulkarni SS, Salehzadeh F, Fritz T, Zierath JR, Krook A, Osler ME. Mitochondrial regulators of fatty acid metabolism reflect metabolic dysfunction in type 2 diabetes mellitus. METABOLISM-CLINICAL AND EXPERIMENTAL 2012 61:2 175-85
59 Long YC, Kostovski E, Boon H, Hjeltnes N, Krook A, Widegren U. Differential expression of metabolic genes essential for glucose and lipid metabolism in skeletal muscle from spinal cord injured subjects. JOURNAL OF APPLIED PHYSIOLOGY 2011 110:5 1204-10
60 Mashili FL, Austin RL, Deshmukh AS, Fritz T, Caidahl K, Bergdahl K, Zierath JR, Chibalin AV, Moller DE, Kharitonenkov A, Krook A. Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity. DIABETES-METABOLISM RESEARCH AND REVIEWS 2011 27:3 286-97
61 Shemyakin A, Salehzadeh F, Duque-Guimaraes DE, Bohm F, Rullman E, Gustafsson T, Pernow J, Krook A. Endothelin-1 Reduces Glucose Uptake in Human Skeletal Muscle In Vivo and In Vitro. DIABETES 2011 60:8 2061-7
62 O'Gorman DJ, Krook A. Exercise and the Treatment of Diabetes and Obesity. MEDICAL CLINICS OF NORTH AMERICA 2011 95:5 953-69
63 Huang-Doran I, Bicknell LS, Finucane FM, Rocha N, Porter KM, Tung YCL, Szekeres F, Krook A, Nolan JJ, O'Driscoll M, Bober M, O'Rahilly S, Jackson AP, Semple RK, Majewski Osteodysplastic Primordia. Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes. DIABETES 2011 60:3 925-35
64 Czepluch FS, Barres R, Caidahl K, Olieslagers S, Krook A, Rickenlund A, Zierath JR, Waltenberger J. Strenuous physical exercise adversely affects monocyte chemotaxis. THROMBOSIS AND HAEMOSTASIS 2011 105:1 122-30
65 Kulkarni SS, Karlsson HKR, Szekeres F, Chibalin AV, Krook A, Zierath JR. Suppression of 5 '-Nucleotidase Enzymes Promotes AMP-activated Protein Kinase (AMPK) Phosphorylation and Metabolism in Human and Mouse Skeletal Muscle. JOURNAL OF BIOLOGICAL CHEMISTRY 2011 286:40 34567-74
66 Shemyakin A, Salehzadeh F, Bohm F, Al-Khalili L, Gonon A, Wagner H, Efendic S, Krook A, Pernow J. Regulation of Glucose Uptake by Endothelin-1 in Human Skeletal Muscle in Vivo and in Vitro. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2010 95:5 2359-66
67 Salehzadeh F, Al-Khalili L, Kulkarni SS, Wang MH, Lonnqvist F, Krook A. Glucocorticoid-mediated effects on metabolism are reversed by targeting 11 beta hydroxysteroid dehydrogenase type 1 in human skeletal muscle. DIABETES-METABOLISM RESEARCH AND REVIEWS 2009 25:3 250-8
68 Barres R, Osler ME, Yan J, Rune A, Fritz T, Caidahl K, Krook A, Zierath JR. Non-CpG Methylation of the PGC-1 alpha Promoter through DNMT3B Controls Mitochondrial Density. CELL METABOLISM 2009 10:3 189-98
69 Chibalin AV, Leng Y, Vieira E, Krook A, Bjoernholm M, Long YC, Kotova O, Zhong ZH, Sakane F, Steiler T, Nylen C, Wang JJ, Laakso M, Topham MK, Gilbert M, Wallberg-Henriksson H, Zierath JR. Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance. CELL 2008 132:3 375-86
70 Bouzakri K, Austin R, Rune A, Lassman ME, Garcia-Roves PM, Berger JP, Krook A, Chibalin AV, Zhang BB, Zierath JR. Malonyl coenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle. DIABETES 2008 57:6 1508-16
71 Glund S, Krook A. Role of interleukin-6 signalling in glucose and lipid metabolism. ACTA PHYSIOLOGICA 2008 192:1 37-48
72 Austin RL, Rune A, Bouzakri K, Zierath JR, Krook A. SiRNA-mediated reduction of inhibitor of nuclear factor-kappa B kinase prevents tumor necrosis factor-alpha-induced insulin resistance in human skeletal muscle. DIABETES 2008 57:8 2066-73
73 Glund S, Deshmukh A, Long YC, Moller T, Koistinen HA, Caidahl K, Zierath JR, Krook A. Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle. DIABETES 2007 56:6 1630-7
74 Kramer DK, Al-Khalili L, Guigas B, Leng Y, Garcia-Roves PM, Krook A. Role of AMP kinase and PPAR delta in the regulation of lipid and glucose metabolism in human skeletal muscle. JOURNAL OF BIOLOGICAL CHEMISTRY 2007 282:27 19313-20
75 Krook A, Long YC, Zierath JR. Skeletal muscle AMP kinase as a target to prevent pathogenesis of Type 2 diabetes. Expert review of endocrinology & metabolism 2007 2:4 477-485
76 Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Bjornholm M, Tornqvist H, Zierath JR, Ridderstrale M, Altshuler D, Lee RT, Vaag A, Groop LC, Mootha VK. TXNIP regulates peripheral glucose metabolism in humans. PLOS MEDICINE 2007 4:5 e158-
77 Kramer DK, Ahlsen M, Norrbom J, Jansson E, Hjeltnes N, Gustafsson T, Krook A. Human skeletal muscle fibre type variations correlate with PPAR alpha, PPAR delta and PGC-1 alpha mRNA. ACTA PHYSIOLOGICA 2006 188:3-4 207-16
78 Fritz T, Kramer DK, Karlsson HKR, Galuska D, Engfeldt P, Zierath JR, Krook A. Low-intensity exercise increases sketelal muscle protein expression of PPAR delta and UCP3 in type 2 diabetic patients. DIABETES-METABOLISM RESEARCH AND REVIEWS 2006 22:6 492-8
79 Al-Khalili L, Bouzakri K, Glund S, Lonnqvist F, Koistinen HA, Krook A. Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle. MOLECULAR ENDOCRINOLOGY 2006 20:12 3364-75
80 Bouzakri K, Zachrisson A, Al-Khalili L, Zhang BB, Koistinen HA, Krook A, Zierath JR. siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. CELL METABOLISM 2006 4:1 89-96
81 Kramer DK, Al-Khalili L, Perrini S, Skogsberg J, Wretenberg P, Kannisto K, Wallberg-Henriksson H, Ehrenborg E, Zierath JR, Krook A. Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta. DIABETES 2005 54:4 1157-63
82 Kramer DK, Bouzakri K, Holmqvist O, Al-Khalili L, Krook A. Effect of serum replacement with Plysate on cell growth and metabolism in primary cultures of human skeletal muscle. CYTOTECHNOLOGY 2005 48:1-3 89-95
83 Al-Khalili L, Forsgren M, Kannisto K, Zierath J, Lonnqvist F, Krook A. Enhanced insulin-stimulated glycogen synthesis in response to insulin, metformin or rosiglitazone is associated with increased mRNA expression of GLUT4 and peroxisomal proliferator activator receptor gamma co-activator 1. DIABETOLOGIA 2005 48:6 1173-9
84 Karlsson HKR, Zierath JR, Kane S, Krook A, Lienhard GE, Wallberg-Henriksson H. Insulin-stimulated phosphorylation of the Akt substrate AS160 is impaired in skeletal muscle of type 2 diabetic subjects. DIABETES 2005 54:6 1692-7
85 Al-Khalili L, Kotova O, Tsuchida H, Ehren I, Feraille E, Krook A, Chibalin AV. ERK1/2 mediates insulin stimulation of Na,K-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells. JOURNAL OF BIOLOGICAL CHEMISTRY 2004 279:24 25211-8
86 Mahlapuu M, Johansson C, Lindgren K, Hjalm G, Barnes BR, Krook A, Zierath JR, Andersson L, Marklund S. Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma 3 in white skeletal muscle. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 2004 286:2 E194-200
87 Al-Khalili L, Kramer D, Wretenberg P, Krook A. Human skeletal muscle cell differentiation is associated with changes in myogenic markers and enhanced insulin-mediated MAPK and PKB phosphorylation. ACTA PHYSIOLOGICA SCANDINAVICA 2004 180:4 395-403
88 Al-Khalili L, Chibalin AV, Yu M, Sjodin B, Nylen C, Zierath JR, Krook A. MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 2004 286:6 C1410-6
89 Al-Khalili L, Krook A, Zierath JR, Cartee GD. Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 2004 287:3 E553-7
90 Karlsson HKR, Tsuchida H, Lake S, Koistinen HA, Krook A. Relationship between serum amyloid A level and Tanis/SelS mRNA expression in skeletal muscle and adipose tissue from healthy and type 2 diabetic subjects. DIABETES 2004 53:6 1424-8
91 Krook A, Wallberg-Henriksson H, Zierath JR. Sending the signal: Molecular mechanisms regulating glucose uptake. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE 2004 36:7 1212-7
92 Al-Khalili L, Chibalin AV, Kannisto K, Zhang BB, Permert J, Holman GD, Ehrenborg E, Ding VDH, Zierath JR, Krook A. Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content. CELLULAR AND MOLECULAR LIFE SCIENCES 2003 60:5 991-8
93 Kemppainen J, Tsuchida H, Stolen K, Karlsson H, Bjornholm M, Heinonen OJ, Nuutila P, Krook A, Knuuti J, Zierath JR. Insulin signalling and resistance in patients with chronic heart failure. JOURNAL OF PHYSIOLOGY-LONDON 2003 550:1 305-15
94 Yu M, Stepto NK, Chibalin AV, Fryer LGD, Carling D, Krook A, Hawley JA, Zierath JR. Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise. JOURNAL OF PHYSIOLOGY-LONDON 2003 546:2 327-35
95 Al-Khalili L, Krook A, Chibalin AV, Jorgensen PL, Karlish SJD, Maunsbach AB. Phosphorylation of the Na+,K+-ATPase in skeletal muscle - Potential mechanism for changes in pump cell-surface abundance and activity. NA,K-ATPASE AND RELATED CATION PUMPS 2003 986: 449-52
96 Krook A, Holm I, Pettersson S, Wallberg-Henriksson H. Reduction of risk factors following lifestyle modification programme in subjects with type 2 (non-insutin dependent) diabetes mellitus. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING 2003 23:1 21-30
97 Al-Khalili L, Cartee GD, Krook A. RNA interface-mediated reduction in GLUT1 inhibits serum-induced glucose transport in primary human skeletal muscle cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2003 307:1 127-32
98 Tsuchida H, Bjornholm M, Fernstrom M, Galuska D, Johansson P, Wallberg-Henriksson H, Zierath JR, Lake S, Krook A. Gene expression of the p85 alpha regulatory subunit of phosphatidylinositol 3-kinase in skeletal muscle from type 2 diabetic subjects. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY 2002 445:1 25-31
99 Kawano Y, Ryder JW, Rincon J, Zierath JR, Krook A, Wallberg-Henriksson H. Evidence against high glucose as a mediator of ERK1/2 or p38 MAPK phosphorylation in rat skeletal muscle. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 2001 281:6 E1255-9
100 Yu M, Blomstrand E, Chibalin AV, Wallberg-Henriksson H, Zierath JR, Krook A. Exercise-associated differences in an array of proteins involved in signal transduction and glucose transport. JOURNAL OF APPLIED PHYSIOLOGY 2001 90:1 29-34
101 Yu M, Blomstrand E, Chibalin AV, Krook A, Zierath JR. Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle. JOURNAL OF PHYSIOLOGY-LONDON 2001 536:1 273-82
102 Krook A, Bjornholm M, Galuska D, Jiang XJ, Fahlman R, Myers MG, Wallberg-Henriksson H, Zierath JR. Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients. DIABETES 2000 49:2 284-92
103 Ryder JW, Fahlman R, Wallberg-Henriksson H, Alessi DR, Krook A, Zierath JR. Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle - Involvement of the mitogen- and stress-activated protein kinase 1. JOURNAL OF BIOLOGICAL CHEMISTRY 2000 275:2 1457-62
104 Krook A, Widegren U, Jiang XJ, Henriksson J, Wallberg-Henriksson H, Alessi D, Zierath JR. Effects of exercise on mitogen- and stress-activated kinase signal transduction in human skeletal muscle. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 2000 279:5 R1716-21
105 Tonkonogi M, Krook A, Walsh B, Sahlin K. Endurance training increases stimulation of uncoupling of skeletal muscle mitochondria in humans by non-esterified fatty acids: an uncoupling-protein-mediated effect?. BIOCHEMICAL JOURNAL 2000 351: 805-10
106 Chibalin AV, Yu M, Ryder JW, Song XM, Galuska D, Krook A, Wallberg-Henriksson H, Zierath JR. Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: Differential effects on insulin-receptor substrates 1 and 2. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 2000 97:1 38-43
107 Ryder JW, Yang J, Galuska D, Rincon J, Bjornholm M, Krook A, Lund S, Pedersen O, Wallberg-Henriksson H, Zierath JR, Holman GD. Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients. DIABETES 2000 49:4 647-54
108 . 35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. Diabetologia 1999 42:Suppl 1 A1-A330
109 Rincon J, Krook A, Galuska D, Wallberg-Henriksson H, Zierath JR. Altered skeletal muscle glucose transport and blood lipid levels in habitual cigarette smokers. CLINICAL PHYSIOLOGY 1999 19:2 135-42
110 Song XM, Kawano Y, Krook A, Ryder JW, Efendic S, Roth RA, Wallberg-Henriksson H, Zierath JR. Muscle fiber type-specific defects in insulin signal transduction to glucose transport in diabetic GK rats. DIABETES 1999 48:3 664-70
111 Song XM, Ryder JW, Kawano Y, Chibalin AV, Krook A, Zierath JR. Muscle fiber type specificity in insulin signal transduction. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 1999 277:6 R1690-6
112 Hjeltnes N, Fernstrom M, Zierath JR, Krook A. Regulation of UCP2 and UCP3 by muscle disuse and physical activity in tetraplegic subjects. DIABETOLOGIA 1999 42:7 826-30
113 Widegren U, Jiang XJ, Krook A, Chibalin AV, Bjornholm M, Tally M, Roth RA, Henriksson J, Wallberg-Henriksson H, Zierath JR. Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle. FASEB JOURNAL 1998 12:13 1379-89
114 Zierath JR, Krook A, Wallberg-Henriksson H. Insulin action in skeletal muscle from patients with NIDDM. MOLECULAR AND CELLULAR BIOCHEMISTRY 1998 182:1-2 153-60
115 Krook A, Roth RA, Jiang XJ, Zierath JR, Wallberg-Henriksson H. Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects. DIABETES 1998 47:8 1281-6
116 Whitehead JP, Humphreys P, Krook A, Jackson R, Hayward A, Lewis H, Siddle K, O'Rahilly S. Molecular scanning of the insulin receptor substrate 1 gene in subjects with severe insulin resistance - Detection and functional analysis of a naturally occurring mutation in a YMXM motif. DIABETES 1998 47:5 837-9
117 Krook A, Digby J, O'Rahilly S, Zierath JR, Wallberg-Henriksson H. Uncoupling protein 3 is reduced in skeletal muscle of NIDDM patients. DIABETES 1998 47:9 1528-31
118 Bevan AP, Krook A, Tikerpae J, Seabright PJ, Siddle K, Smith GD. Chloroquine extends the lifetime of the activated insulin receptor complex in endosomes. JOURNAL OF BIOLOGICAL CHEMISTRY 1997 272:43 26833-40
119 Zaidi FK, Wareham NJ, McCarthy MI, Holdstock J, KallooHosein H, Krook A, Swinn RA, ORahilly S. Homozygosity for a common polymorphism in the islet-specific promoter of the glucokinase gene is associated with a reduced early insulin response to oral glucose in pregnant women. DIABETIC MEDICINE 1997 14:3 228-34
120 Krook A, Kawano Y, Song XM, Efendic S, Roth RA, WallbergHenriksson H, Zierath JR. Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats. DIABETES 1997 46:12 2110-4
121 Krook A, Whitehead JP, Dobson SP, Griffiths MR, Ouwens M, Baker C, Hayward AC, Sen SK, Maassen JA, Siddle K, Tavare JM, ORahilly S. Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects. JOURNAL OF BIOLOGICAL CHEMISTRY 1997 272:48 30208-14
122 Krook A, Soos MA, Kumar S, Siddle K, ORahilly S. Functional activation of mutant human insulin receptor by monoclonal antibody. LANCET 1996 347:9015 1586-90
123 ORahilly S, Krook A, Humphreys PJ, Whitehead J. Insights into insulin signalling from naturally-occurring mutations in the insulin signal transduction pathway.. QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS 1996 89:11 874-874
124 Talbot JA, Bicknell EJ, Rajkhowa M, Krook A, ORahilly S, Clayton RN. Molecular scanning of the insulin receptor gene in women with polycystic ovarian syndrome. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 1996 81:5 1979-83
125 Krook A, Moller DE, Dib K, ORahilly S. Two naturally occurring mutant insulin receptors phosphorylate insulin receptor substrate-1 (IRS-1) but fail to mediate the biological effects of insulin - Evidence that IRS-1 phosphorylation is not sufficient for normal insulin action. JOURNAL OF BIOLOGICAL CHEMISTRY 1996 271:12 7134-40
126 ORAHILLY S, GRAY H, HUMPHREYS PJ, KROOK A, POLONSKY KS, WHITE A, GIBSON S, TAYLOR K, CARR C. IMPAIRED PROCESSING OF PROHORMONES ASSOCIATED WITH ABNORMALITIES OF GLUCOSE-HOMEOSTASIS AND ADRENAL-FUNCTION. NEW ENGLAND JOURNAL OF MEDICINE 1995 333:21 1386-90
127 KROOK A, BELL JA, ROBERTSON ME, BRUETON L. PRENATAL ANALYSIS OF THE INSULIN-RECEPTOR GENE IN A FAMILY WITH LEPRECHAUNISM. PRENATAL DIAGNOSIS 1995 15:7 669-71

Review

1 Stover PJ, James WPT, Krook A, Garza C. Emerging concepts on the role of epigenetics in the relationships between nutrition and health. Journal of internal medicine 2018 284:1 37-49
2 Kirchner H, Osler ME, Krook A, Zierath JR. Epigenetic flexibility in metabolic regulation: disease cause and prevention?. Trends in cell biology 2013 23:5 203-9
3 Zierath JR, Krook A. [Molecular mechanisms underlying insulin resistance in skeletal muscle]. Lakartidningen 2010 107:45 2802-5
4 Ehrenborg E, Krook A. Regulation of Skeletal Muscle Physiology and Metabolism by Peroxisome Proliferator-Activated Receptor delta. PHARMACOLOGICAL REVIEWS 2009 61:3 373-93
5 Krook A, Zierath JR. Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA. DIABETOLOGIA 2009 52:7 1231-9
6 O'Gorman DJ, Krook A. Exercise and the Treatment of Diabetes and Obesity. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA 2008 37:4 887-903
7 Lake S, Krook A, Zierath JR. Analysis of insulin signaling pathways through comparative genomics. Mapping mechanisms for insulin resistance in type 2 (non-insulin-dependent) diabetes mellitus. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES 2003 111:4 191-7
8 Zierath JR, Krook A, Wallberg-Henriksson H. Insulin action and insulin resistance in human skeletal muscle. DIABETOLOGIA 2000 43:7 821-35
9 Baynes KCR, Whitehead J, Krook A, ORahilly S. Molecular mechanisms of inherited insulin resistance. QJM-MONTHLY JOURNAL OF THE ASSOCIATION OF PHYSICIANS 1997 90:9 557-62
10 Krook A, ORahilly S. Mutant insulin receptors in syndromes of insulin resistance. BAILLIERES CLINICAL ENDOCRINOLOGY AND METABOLISM 1996 10:1 97-122

Editorial

1 Alm PS, Krook A, Barbosa TD. Maternal obesity legacy: exercise it away!. DIABETOLOGIA 2016 59:1 5-8
2 Hawley JA, Krook A. Metabolism: One step forward for exercise. Nature reviews. Endocrinology 2016 12:1 7-8
3 Nair KS, Abel ED, Adler SG, Dyck PJ, Gardner TW, Haskins KM, Hotamisligil G, Jensen MD, Krook A, Mandarino LJ, Mitchell BD, Pessin JE, Sowers JR, Sussel L, Wareham N, Vella A. Time to Look Back and to Look Forward. DIABETES 2014 63:4 1169-70
4 Lundell LS, Krook A. ContRac1ion-mediated glucose uptake: a central role for Rac1. Diabetes 2013 62:4 1024-5
5 Mannerås-Holm L, Krook A. Targeting adipose tissue angiogenesis to enhance insulin sensitivity. Diabetologia 2012 55:10 2562-2564
6 Krook A. A balancing act of optimising insulin dose and insulin sensitivity in type 1 diabetes. JOURNAL OF ENDOCRINOLOGY 2011 211:1 1-2
7 Krook A. IL-6 and metabolism - new evidence and new questions. DIABETOLOGIA 2008 51:7 1097-9
8 Krook A. Can the liver X receptor work its magic in skeletal muscle too?. DIABETOLOGIA 2006 49:5 819-21
9 Krook A, ORahilly S. Homozygous mutation in the insulin receptor. CLINICAL ENDOCRINOLOGY 1996 45:2 237-8

Other

1 Mudry JM, Massart J, Szekeres FL, Krook A. TWIST1 and TWIST2 regulate glycogen storage and inflammatory genes in skeletal muscle. The Journal of endocrinology 2015 226:3 X1-
2 Barres R, Kirchner H, Rasmussen M, Yan J, Kantor FR, Krook A, Naslund E, Zierath JR. Weight Loss after Gastric Bypass Surgery in Human Obesity Remodels Promoter Methylation (vol 3, pg 1020, 2013). CELL REPORTS 2013 3:5 1755-1755
3 Long YC, Kostovski E, Boon H, Hjeltnes N, Krook A, Widegren U. Differential expression of metabolic genes essential for glucose and lipid metabolism in skeletal muscle from spinal cord injured subjects (vol 110, pg 1204, 2011). JOURNAL OF APPLIED PHYSIOLOGY 2011 111:2 622-622
4 Mashili FL, Austin RL, Deshkmukh AS, Fritz T, Caidahl K, Bergdahl K, Juleen ZR, Moller DE, Kharitonenkov A, Krook A. Direct effects of FGF 21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity. DIABETOLOGIA 2010 53:
5 Shemyakin A, Salehzadeh F, Guimaraes DD, Bohm F, Rullman E, Gustafsson T, Pernow J, Krook A. Endothelin-1 acutely affects glucose metabolism in human skeletal muscle. DIABETOLOGIA 2010 53: S80-S80
6 Kulkarni SS, Karlsson HKR, Krook A, Zierath JR. Suppression of the 5 ' nucleotidase NT5C2 promotes AMPK phosphorylation and lipid oxidation in human skeletal muscle. DIABETOLOGIA 2010 53:
7 Yan J, Barres R, Krook A, Naslund E, Zierath JR. Weight loss modulates DNA methylation of peroxisome proliferator-activated receptor gamma coactivator-1 and pyruvate dehydrogenase. DIABETOLOGIA 2010 53: S43-S43
8 Kramer DK, Ahlsen M, Norrbom J, Jansson E, Hjeltnes N, Gustafsson T, Krook A. Human skeletal muscle fibre type variations correlate with PPAR (alpha), PPAR delta and PGC-I(alpha) mRNA (vol 188, pg 207, 2006). ACTA PHYSIOLOGICA 2007 189:1 101-101
9 Parikh H, Carlsson E, Chutkow WA, Johansson L, Saxena R, Krook A, Bjornholm M, Zierath J, Ridderstrale M, Altshuler D, Lee RT, Vaag A, Groop LC, Mootha VK. Identification of TXNIP as a marker and regulator of glucose homeostasis in humans. DIABETOLOGIA 2006 49: 21-21
10 Al-Khalili L, Bouzakri K, Glund S, Lonnqvist F, Koistinen HA, Krook A. Signaling specificity of IL6 action on glucose and lipid metabolism in skeletal muscle. DIABETOLOGIA 2006 49: 411-411
11 Zachrisson AK, Bouzakri K, Al-Khalili L, Zhang BB, Koistinen HA, Krook A, Zierath JR. siRNA based gene silencing reveals specialised roles for Akt1 and Akt2 on glucose and lipid metabolism in human skeletal muscle. DIABETOLOGIA 2006 49: 22-22
12 Bouzakri K, Zachrisson A, Al-Khalili L, Zhang BB, Koistinen HA, Krook A, Zierath JR. siRNA based gene silencing reveals specialized roles of IRS-1 and IRS-2 in glucose and lipid metabolism in human skeletal muscle. DIABETOLOGIA 2006 49: 21-22
13 Krook A, Al-Khalili L, Chibalin AV, Wallberg-Henriksson H, Zierath JR. Evidence for 2 distinct pathways for activation of MEF2-DNA binding in primary cultures of human skeletal muscle. DIABETOLOGIA 2002 45: A22-A22
14 Galuska D, Ryder J, Chibalina D, Krook A, Wallberg-Henriksson H, Zierath J, Chibalin A. Exercise prevents high fat feeding-induced changes in expression of Na+, K+-ATPase in rat skeletal muscle.. DIABETOLOGIA 2002 45: A271-A271
15 Tsuchida H, Bjornholm M, Galuska D, Fernstrom M, Johansson P, Wallberg-Henriksson H, Zierath JR, Lake S, Krook A. Gene expression of the p85 alpha regulatory subunit of PI 3-kinase in skeletal muscle from Type 2 diabetic subjects. DIABETOLOGIA 2002 45: A189-A190
16 Krook A, Fernstrom M, Galuska D, Wallberg-Henriksson H, Zierath JR. Elevated gene expression of the p85 alpha regulatory subunit of PI3 kinase in skeletal muscle from type 2 diabetic subjects. DIABETOLOGIA 2000 43: A87-A87
17 Zierath JR, Chibalin AV, Ryder JW, Song XM, Krook A, Wallberg-Henriksson H. Effects of exercise-training on insulin-signalling in skeletal muscle.. DIABETOLOGIA 1999 42: A178-A178
18 Krook A, Jiang XJ, Ryder JW, Alessi DR, Zierath JR. Effects of muscle contractions on glucose metabolism and activation of the MAP kinase cascade.. DIABETOLOGIA 1999 42: A178-A178
19 Bjornholm M, Krook A, Galuska D, Myers M, Zierath JR, Wallberg-Henriksson H. Insulin signalling to metabolic events is impaired in skeletal muscle from people with NIDDM.. DIABETOLOGIA 1999 42: A171-A171
20 Song XM, Krook A, Wallberg-Henriksson H, Zierath JR. Muscle fibre-type specificity in insulin signal transduction.. DIABETOLOGIA 1999 42: A178-A178
21 Bjornholm M, Widegren U, Jiang XJ, Krook A, Tally M, Roth RA, Henriksson J, Wallberg-Henriksson H, Zierath JR. Effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle.. DIABETOLOGIA 1998 41: A263-A263
22 Krook A, Whitehead JP, Dobson S, Tavare J, Ouwens M, Maasen JA, Baker C, ORahilly S. PI3-kinase activation alone is not sufficient for the mediation of insulin action. DIABETOLOGIA 1997 40: 148-148
23 KROOK A, HAIGH RJ, MOLLER DE, DIB K, SIDDLE K, ORAHILLY S. 2 NATURALLY-OCCURRING INSULIN-RECEPTOR MUTATIONS SHOW IMPAIRED SIGNALING DESPITE PHOSPHORYLATION OF INSULIN-RECEPTOR SUBSTRATE. DIABETOLOGIA 1995 38: A69-A69
24 WHITEHEAD JP, HUMPHREYS PJ, MAASEN JA, MOLLER DE, KROOK A, ORAHILLY S. INCREASED PC-1 PHOSPHODIESTERASE ACTIVITY IN PATIENTS WITH POSTRECEPTOR INSULIN-RESISTANCE BUT NOT IN PATIENTS WITH INSULIN-RECEPTOR MUTATIONS. DIABETOLOGIA 1995 38: A65-A65