Publications for Magdalena Paolino

Article

1 Li XY, Sun B, Qian HR, Ma JR, Paolino M, Zhang ZY. A high-efficiency and versatile CRISPR/Cas9-mediated HDR-based biallelic editing system. JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B 2022 23:2 141-152
2 Paolino M, Koglgruber R, Cronin SJF, Uribesalgo I, Rauscher E, Harreiter J, Schuster M, Bancher-Todesca D, Pranjic B, Novatchkova M, Fededa JP, White AJ, Sigl V, Dekan S, Penz T, Bock C, Kenner L, Hollander GA, Anderson G, Kautzky-Willer A, Penninger JM. RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy. NATURE 2021 589:7843 442-447
3 Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM. The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 2018 563:7732 564-568
4 Suriben R, Kaihara KA, Paolino M, Reichelt M, Kummerfeld SK, Modrusan Z, Dugger DL, Newton K, Sagolla M, Webster JD, Liu J, Hebrok M, Dixit VM. β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1. Cell 2015 163:6 1457-67
5 Paolino M, Choidas A, Wallner S, Pranjic B, Uribesalgo I, Loeser S, Jamieson AM, Langdon WY, Ikeda F, Fededa JP, Cronin SJ, Nitsch R, Schultz-Fademrecht C, Eickhoff J, Menninger S, Unger A, Torka R, Gruber T, Hinterleitner R, Baier G, Wolf D, Ullrich A, Klebl BM, Penninger JM. The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature 2014 507:7493 508-12
6 Agrelo R, Kishimoto H, Novatchkova M, Peraza V, Paolino M, Souabni A, Wutz A. SATB1 collaborates with loss of p16 in cellular transformation. Oncogene 2013 32:48 5492-500
7 Hashimoto T, Perlot T, Rehman A, Trichereau J, Ishiguro H, Paolino M, Sigl V, Hanada T, Hanada R, Lipinski S, Wild B, Camargo SM, Singer D, Richter A, Kuba K, Fukamizu A, Schreiber S, Clevers H, Verrey F, Rosenstiel P, Penninger JM. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature 2012 487:7408 477-81
8 Roberts NA, White AJ, Jenkinson WE, Turchinovich G, Nakamura K, Withers DR, McConnell FM, Desanti GE, Benezech C, Parnell SM, Cunningham AF, Paolino M, Penninger JM, Simon AK, Nitta T, Ohigashi I, Takahama Y, Caamano JH, Hayday AC, Lane PJ, Jenkinson EJ, Anderson G. Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium. Immunity 2012 36:3 427-37
9 Paolino M, Thien CB, Gruber T, Hinterleitner R, Baier G, Langdon WY, Penninger JM. Essential role of E3 ubiquitin ligase activity in Cbl-b-regulated T cell functions. Journal of immunology (Baltimore, Md. : 1950) 2011 186:4 2138-47
10 Hanada R, Leibbrandt A, Hanada T, Kitaoka S, Furuyashiki T, Fujihara H, Trichereau J, Paolino M, Qadri F, Plehm R, Klaere S, Komnenovic V, Mimata H, Yoshimatsu H, Takahashi N, von Haeseler A, Bader M, Kilic SS, Ueta Y, Pifl C, Narumiya S, Penninger JM. Central control of fever and female body temperature by RANKL/RANK. Nature 2009 462:7272 505-9
11 Paolino M, Penninger JM. E3 ubiquitin ligases in T-cell tolerance. European journal of immunology 2009 39:9 2337-44
12 Fayard E, Gill J, Paolino M, Hynx D, Holländer GA, Hemmings BA. Deletion of PKBalpha/Akt1 affects thymic development. PloS one 2007 2:10 e992-

Review

1 Gavali S, Liu J, Li X, Paolino M. Ubiquitination in T-Cell Activation and Checkpoint Inhibition: New Avenues for Targeted Cancer Immunotherapy. International journal of molecular sciences 2021 22:19
2 Paolino M, Penninger JM. The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer Therapy. Cancers 2016 8:10
3 Paolino M, Penninger JM. Cbl-b in T-cell activation. Seminars in immunopathology 2010 32:2 137-48