Publications for Lars Sävendahl

Article

1	Velentza L, Wickström M, Kogner P, Ohlsson C, Zaman F, Sävendahl L. Humanin Treatment Protects Against Venetoclax-Induced Bone Growth Retardation in Ex Vivo Cultured Rat Bones. Journal of the Endocrine Society 2024 8:3 bvae009- View record in PubMed® Fulltext: https://doi.org/10.1210/jendso/bvae009
2	Tidblad A, Bottai M, Smedby KE, Albertsson-Wikland K, Sävendahl L. Long-term risk of neoplastic events after childhood growth hormone treatment: a population-based cohort study in Sweden. Frontiers in endocrinology 2024 15: 1360139- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.3389/fendo.2024.1360139
3	Aeppli TR, Benyi E, Wehtje H, Chrysis D, Sävendahl L. Safety and Efficacy of Bilateral Epiphysiodesis Surgery to Reduce Final Height in Extremely Tall Adolescents - A Follow-up Study. Hormone research in paediatrics 2024 : View record in PubMed® Fulltext: https://doi.org/10.1159/000538016
4	Zhao Y, Mäkitie O, Laakso S, Fedosova V, Sävendahl L, Zaman F. A novel link between chronic inflammation and humanin regulation in children. Frontiers in endocrinology 2023 14: 1142310- View record in PubMed® Fulltext: https://doi.org/10.3389/fendo.2023.1142310
5	Chen SC, Bryce J, Chen M, Charmandari E, Choi JH, Dou X, Gong C, Hamza R, Harvey J, Hoffman AR, Horikawa R, Johannson G, Jorge AAL, Miller BS, Roehrich S, Sävendahl L, Tseretopoulou X, Vitali D, Wajnrajch M, Ahmed SF. Development of A Minimum Dataset for the Monitoring of Recombinant Human Growth Hormone (rhGH) Therapy Use in Children with Growth Hormone Deficiency (GHD) - A GloBE-Reg Initiative. Hormone research in paediatrics 2023 : View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000533763
6	Backeljauw P, Blair JC, Ferran JM, Kelepouris N, Miller BS, Pietropoli A, Polak M, Sävendahl L, Verlinde F, Rohrer TR. Early GH Treatment Is Effective and Well Tolerated in Children With Turner Syndrome: NordiNet® IOS and Answer Program. The Journal of clinical endocrinology and metabolism 2023 108:10 2653-2665 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/clinem/dgad159
7	Smew AI, Lundholm C, Gong T, Sävendahl L, Lichtenstein P, Brew BK, Almqvist C. Maternal depression or anxiety during pregnancy and offspring type 1 diabetes: a population-based family-design cohort study. BMJ open diabetes research & care 2023 11:2 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1136/bmjdrc-2023-003303
8	Zhang ZP, Zaman F, Nava TS, Aeppli TRJ, Gutierrez-Farewik EM, Kulachenko A, Savendahl L. Micromechanical Loading Studies in Ex Vivo Cultured Embryonic Rat Bones Enabled by a Newly Developed Portable Loading Device. ANNALS OF BIOMEDICAL ENGINEERING 2023 51:10 2229-2236 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1007/s10439-023-03258-2
9	Velentza L, Wickström M, Kogner P, Ohlsson C, Zaman F, Sävendahl L. Pharmacological inhibition of BCL-2 with the FDA-approved drug venetoclax impairs longitudinal bone growth. Scientific reports 2023 13:1 8054- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/s41598-023-34965-4
10	Mistry JN, Silvennoinen S, Zaman F, Sävendahl L, Mariniello K, Hall C, Howard SR, Dunkel L, Sankilampi U, Guasti L. The crosstalk between FGF21 and GH leads to weakened GH receptor signaling and IGF1 expression and is associated with growth failure in very preterm infants. Frontiers in endocrinology 2023 14: 1105602- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.3389/fendo.2023.1105602
11	Sävendahl L, Battelino T, Højby Rasmussen M, Brod M, Röhrich S, Saenger P, Horikawa R. Weekly Somapacitan in GH Deficiency: 4-Year Efficacy, Safety, and Treatment/Disease Burden Results From REAL 3. The Journal of clinical endocrinology and metabolism 2023 108:10 2569-2578 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/clinem/dgad183
12	Savendahl L, Battelino T, Rasmussen MH, Brod M, Saenger P, Horikawa R. Effective GH Replacement With Once-weekly Somapacitan vs Daily GH in Children with GHD: 3-year Results From REAL 3. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2022 107:5 1357-1367 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/clinem/dgab928
13	Ramesh S, Zaman F, Sävendahl L, Madhuri V. Radial shockwave treatment promotes chondrogenesis in human growth plate and longitudinal bone growth in rabbits. Bone 2022 154: 116186- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/j.bone.2021.116186
14	Boguszewski MCS, Boguszewski CL, Chemaitilly W, Cohen LE, Gebauer J, Higham C, Hoffman AR, Polak M, Yuen KCJ, Alos N, Antal Z, Bidlingmaier M, Biller BMK, Brabant G, Choong CSY, Cianfarani S, Clayton PE, Coutant R, Cardoso-Demartini AA, Fernandez A, Grimberg A, Guðmundsson K, Guevara-Aguirre J, Ho KKY, Horikawa R, Isidori AM, Jørgensen JOL, Kamenicky P, Karavitaki N, Kopchick JJ, Lodish M, Luo X, McCormack AI, Meacham L, Melmed S, Mostoufi Moab S, Müller HL, Neggers SJCMM, Aguiar Oliveira MH, Ozono K, Pennisi PA, Popovic V, Radovick S, Savendahl L, Touraine P, van Santen HM, Johannsson G. Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement. European journal of endocrinology 2022 186:6 P35-P52 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/EJE-21-1186
15	Zhao Y, Celvin B, Denis MC, Karagianni N, Aulin C, Zaman F, Sävendahl L. TNF overexpression and dexamethasone treatment impair chondrogenesis and bone growth in an additive manner. Scientific reports 2022 12:1 18189- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/s41598-022-22734-8
16	Tidblad A, Bottai M, Kieler H, Albertsson-Wikland K, Savendahl L. Association of Childhood Growth Hormone Treatment With Long-term Cardiovascular Morbidity. JAMA PEDIATRICS 2021 175:2 e205199- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1001/jamapediatrics.2020.5199
17	Lennartsson O, Lodefalk M, Wehtje H, Stattin EL, Sävendahl L, Nilsson O. Case Report: Bilateral Epiphysiodesis Due to Extreme Tall Stature in a Girl With a De Novo DNMT3A Variant Associated With Tatton-Brown-Rahman Syndrome. Frontiers in endocrinology 2021 12: 752756- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.3389/fendo.2021.752756
18	Rohrer TR, Abuzzahab J, Backeljauw P, Birkegard AC, Blair J, Dahlgren J, Juliusson PB, Ostrow V, Pietropoli A, Polak M, Romano A, Ross J, Savendahl L, Miller BS. Long-Term Effectiveness and Safety of Childhood Growth Hormone Treatment in Noonan Syndrome. HORMONE RESEARCH IN PAEDIATRICS 2021 93:6 380-395 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000512429
19	Sävendahl L, Polak M, Backeljauw P, Blair JC, Miller BS, Rohrer TR, Hokken-Koelega A, Pietropoli A, Kelepouris N, Ross J. Long-Term Safety of Growth Hormone Treatment in Childhood: Two Large Observational Studies: NordiNet IOS and ANSWER. The Journal of clinical endocrinology and metabolism 2021 106:6 1728-1741 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/clinem/dgab080
20	Mouratidou N, Malmborg P, Sachs MC, Askling J, Ekbom A, Neovius M, Smedby KE, Sävendahl L, Ludvigsson JF, Olén O. Adult height in patients with childhood-onset inflammatory bowel disease: a nationwide population-based cohort study. Alimentary pharmacology & therapeutics 2020 51:8 789-800 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/apt.15667
21	Smew AI, Lundholm C, Sävendahl L, Lichtenstein P, Almqvist C. Familial Coaggregation of Asthma and Type 1 Diabetes in Children. JAMA network open 2020 3:3 e200834- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1001/jamanetworkopen.2020.0834
22	Mårild K, Ohlsson C, Bygdell M, Martikainen J, Sävendahl L, Størdal K, Kindblom JM. Growth and Pubertal Timing in Boys With Adult-diagnosed Celiac Disease: A Population-based Longitudinal Cohort Study. Journal of pediatric gastroenterology and nutrition 2020 70:6 853-857 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1097/MPG.0000000000002682
23	Celvin B, Zaman F, Aulin C, Sävendahl L. Humanin prevents undesired apoptosis of chondrocytes without interfering with the anti-inflammatory effect of dexamethasone in collagen-induced arthritis. Clinical and experimental rheumatology 2020 38:1 129-135 View record in PubMed® View record in Web of Science®
24	Sävendahl L, Cooke R, Tidblad A, Beckers D, Butler G, Cianfarani S, Clayton P, Coste J, Hokken-Koelega ACS, Kiess W, Kuehni CE, Albertsson-Wikland K, Deodati A, Ecosse E, Gausche R, Giacomozzi C, Konrad D, Landier F, Pfaeffle R, Sommer G, Thomas M, Tollerfield S, Zandwijken GRJ, Carel JC, Swerdlow AJ. Long-term mortality after childhood growth hormone treatment: the SAGhE cohort study. The lancet. Diabetes & endocrinology 2020 8:8 683-692 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/S2213-8587(20)30163-7
25	Sävendahl L, Battelino T, Brod M, Højby Rasmussen M, Horikawa R, Juul RV, Saenger P, REAL 3 study group. Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial. The Journal of clinical endocrinology and metabolism 2020 105:4 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/clinem/dgz310
26	Ramesh S, Zaman F, Madhuri V, Sävendahl L. Radial Extracorporeal Shock Wave Treatment Promotes Bone Growth and Chondrogenesis in Cultured Fetal Rat Metatarsal Bones. Clinical orthopaedics and related research 2020 478:3 668-678 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1097/CORR.0000000000001056
27	Ramesh S, Savendahl L, Madhuri V, Zaman F. Radial shock waves prevent growth retardation caused by the clinically used drug vismodegib in ex vivo cultured bones. SCIENTIFIC REPORTS 2020 10:1 13400- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/s41598-020-69904-0
28	Benyi E, Linder M, Adami J, Kieler H, Palme M, Sävendahl L. Adult height is associated with risk of cancer and mortality in 5.5 million Swedish women and men. Journal of epidemiology and community health 2019 73:8 730-736 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1136/jech-2018-211040
29	Newton PT, Li L, Zhou B, Schweingruber C, Hovorakova M, Xie M, Sun X, Sandhow L, Artemov AV, Ivashkin E, Suter S, Dyachuk V, El Shahawy M, Gritli-Linde A, Bouderlique T, Petersen J, Mollbrink A, Lundeberg J, Enikolopov G, Qian H, Fried K, Kasper M, Hedlund E, Adameyko I, Sävendahl L, Chagin AS. A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate. Nature 2019 567:7747 234-238 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/s41586-019-0989-6
30	Hedman A, Breithaupt L, Hübel C, Thornton LM, Tillander A, Norring C, Birgegård A, Larsson H, Ludvigsson JF, Sävendahl L, Almqvist C, Bulik CM. Bidirectional relationship between eating disorders and autoimmune diseases. Journal of child psychology and psychiatry, and allied disciplines 2019 60:7 803-812 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/jcpp.12958
31	Haffner D, Emma F, Eastwood DM, Duplan MB, Bacchetta J, Schnabel D, Wicart P, Bockenhauer D, Santos F, Levtchenko E, Harvengt P, Kirchhoff M, Di Rocco F, Chaussain C, Brandi ML, Savendahl L, Briot K, Kamenicky P, Rejnmark L, Linglart A. Clinical practice recommendations for the diagnosis and management of X-linked hypophosphataemia. Nature reviews. Nephrology 2019 15:7 435-455 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/s41581-019-0152-5
32	Iravani M, Lagerquist MK, Karimian E, Chagin AS, OhIsson C, Savendahl L. Effects of the selective GPER1 agonist G1 on bone growth. ENDOCRINE CONNECTIONS 2019 8:9 1302-1309 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/EC-19-0274
33	Dahl S, Kristoffersen Wiberg M, Teär Fahnehjelm K, Sävendahl L, Wickström R. High prevalence of pituitary hormone deficiency in both unilateral and bilateral optic nerve hypoplasia. Acta paediatrica (Oslo, Norway : 1992) 2019 108:9 1677-1685 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/apa.14751
34	Zaman F, Zhao Y, Celvin B, Mehta HH, Wan J, Chrysis D, Ohlsson C, Fadeel B, Cohen P, Sävendahl L. Humanin is a novel regulator of Hedgehog signaling and prevents glucocorticoid-induced bone growth impairment. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 33:4 4962-4974 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1096/fj.201801741R
35	Swerdlow AJ, Cooke R, Beckers D, Butler G, Carel JC, Cianfarani S, Clayton P, Coste J, Deodati A, Ecosse E, Hokken-Koelega ACS, Khan AJ, Kiess W, Kuehni CE, Flück CE, Pfaffle R, Sävendahl L, Sommer G, Thomas M, Tidblad A, Tollerfield S, Zandwijken GRJ. Risk of Meningioma in European Patients Treated With Growth Hormone in Childhood: Results From the SAGhE Cohort. The Journal of clinical endocrinology and metabolism 2019 104:3 658-664 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jc.2018-01133
36	Ohlsson C, Bygdell M, Celind J, Sonden A, Tidblad A, Savendahl L, Kindblom JM. Secular Trends in Pubertal Growth Acceleration in Swedish Boys Born From 1947 to 1996. JAMA PEDIATRICS 2019 173:9 860-865 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1001/jamapediatrics.2019.2315
37	Savendahl L, Polak M, Backeljauw P, Blair J, Miller BS, Rohrer TR, Pietropoli A, Ostrow V, Ross J. Treatment of Children With GH in the United States and Europe: Long-Term Follow-Up From NordiNet (R) IOS and ANSWER Program. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2019 104:10 4730-4742 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jc.2019-00775
38	Newton PT, Xie M, Medvedeva EV, Sävendahl L, Chagin AS. Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered. Bone reports 2018 8: 64-71 View record in PubMed® Fulltext: https://doi.org/10.1016/j.bonr.2018.02.006
39	Swerdlow AJ, Cooke R, Beckers D, Borgström B, Butler G, Carel JC, Cianfarani S, Clayton P, Coste J, Deodati A, Ecosse E, Gausche R, Giacomozzi C, Hokken-Koelega ACS, Khan AJ, Kiess W, Kuehni CE, Mullis PE, Pfaffle R, Sävendahl L, Sommer G, Thomas M, Tidblad A, Tollerfield S, Van Eycken L, Zandwijken GRJ. Cancer Risks in Patients Treated With Growth Hormone in Childhood: The SAGhE European Cohort Study. The Journal of clinical endocrinology and metabolism 2017 102:5 1661-1672 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jc.2016-2046
40	Iravani M, Lagerquist M, Ohlsson C, Sävendahl L. Regulation of bone growth via ligand-specific activation of estrogen receptor alpha. The Journal of endocrinology 2017 232:3 403-410 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/JOE-16-0263
41	Battelino T, Rasmussen MH, De Schepper J, Zuckerman-Levin N, Gucev Z, Sävendahl L, NN8640-4042 Study Group. Somapacitan, a once-weekly reversible albumin-binding GH derivative, in children with GH deficiency: A randomized dose-escalation trial. Clinical endocrinology 2017 87:4 350-358 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/cen.13409
42	Allen DB, Backeljauw P, Bidlingmaier M, Biller BM, Boguszewski M, Burman P, Butler G, Chihara K, Christiansen J, Cianfarani S, Clayton P, Clemmons D, Cohen P, Darendeliler F, Deal C, Dunger D, Erfurth EM, Fuqua JS, Grimberg A, Haymond M, Higham C, Ho K, Hoffman AR, Hokken-Koelega A, Johannsson G, Juul A, Kopchick J, Lee P, Pollak M, Radovick S, Robison L, Rosenfeld R, Ross RJ, Savendahl L, Saenger P, Sorensen HT, Stochholm K, Strasburger C, Swerdlow A, Thorner M. GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults. European journal of endocrinology 2016 174:2 P1-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/EJE-15-0873
43	Munns CF, Shaw N, Kiely M, Specker BL, Thacher TD, Ozono K, Michigami T, Tiosano D, Mughal MZ, Mäkitie O, Ramos-Abad L, Ward L, DiMeglio LA, Atapattu N, Cassinelli H, Braegger C, Pettifor JM, Seth A, Idris HW, Bhatia V, Fu J, Goldberg G, Sävendahl L, Khadgawat R, Pludowski P, Maddock J, Hyppönen E, Oduwole A, Frew E, Aguiar M, Tulchinsky T, Butler G, Högler W. Global Consensus Recommendations on Prevention and Management of Nutritional Rickets. The Journal of clinical endocrinology and metabolism 2016 101:2 394-415 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jc.2015-2175
44	Munns CF, Shaw N, Kiely M, Specker BL, Thacher TD, Ozono K, Michigami T, Tiosano D, Mughal MZ, Mäkitie O, Ramos-Abad L, Ward L, DiMeglio LA, Atapattu N, Cassinelli H, Braegger C, Pettifor JM, Seth A, Idris HW, Bhatia V, Fu J, Goldberg G, Sävendahl L, Khadgawat R, Pludowski P, Maddock J, Hyppönen E, Oduwole A, Frew E, Aguiar M, Tulchinsky T, Butler G, Högler W. Global Consensus Recommendations on Prevention and Management of Nutritional Rickets. Hormone research in paediatrics 2016 85:2 83-106 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000443136
45	Sävendahl L, Pournara E, Pedersen BT, Blankenstein O. Is safety of childhood growth hormone therapy related to dose? Data from a large observational study. European journal of endocrinology 2016 174:5 681-91 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/EJE-15-1017
46	Albertsson-Wikland K, Mårtensson A, Sävendahl L, Niklasson A, Bang P, Dahlgren J, Gustafsson J, Kriström B, Norgren S, Pehrsson NG, Odén A. Mortality Is Not Increased in Recombinant Human Growth Hormone-treated Patients When Adjusting for Birth Characteristics. The Journal of clinical endocrinology and metabolism 2016 101:5 2149-59 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jc.2015-3951
47	Hannema SE, Sävendahl L. The Evaluation and Management of Tall Stature. Hormone research in paediatrics 2016 85:5 347-52 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000443685
48	Swerdlow AJ, Cooke R, Albertsson-Wikland K, Borgström B, Butler G, Cianfarani S, Clayton P, Coste J, Deodati A, Ecosse E, Gausche R, Giacomozzi C, Kiess W, Hokken-Koelega AC, Kuehni CE, Landier F, Maes M, Mullis PE, Pfaffle R, Sävendahl L, Sommer G, Thomas M, Tollerfield S, Zandwijken GR, Carel JC. Description of the SAGhE Cohort: A Large European Study of Mortality and Cancer Incidence Risks after Childhood Treatment with Recombinant Growth Hormone. Hormone research in paediatrics 2015 84:3 172-83 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000435856
49	Cedervall T, Lind PM, Sävendahl L. Expression of the aryl hydrocarbon receptor in growth plate cartilage and the impact of its local modulation on longitudinal bone growth. International journal of molecular sciences 2015 16:4 8059-69 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.3390/ijms16048059
50	Reynaert N, Ockeloen CW, Sävendahl L, Beckers D, Devriendt K, Kleefstra T, Carels CE, Grigelioniene G, Nordgren A, Francois I, de Zegher F, Casteels K. Short Stature in KBG Syndrome: First Responses to Growth Hormone Treatment. Hormone research in paediatrics 2015 83:5 361-4 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000380908
51	Hou M, Eriksson E, Svechnikov K, Jahnukainen K, Söder O, Meinhardt A, Sävendahl L. Bortezomib treatment causes long-term testicular dysfunction in young male mice. Molecular cancer 2014 13: 155- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1186/1476-4598-13-155
52	Sundström K, Cedervall T, Ohlsson C, Camacho-Hübner C, Sävendahl L. Combined treatment with GH and IGF-I: additive effect on cortical bone mass but not on linear bone growth in female rats. Endocrinology 2014 155:12 4798-807 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/en.2014-1160
53	Liu F, Hendriks AE, Ralf A, Boot AM, Benyi E, Sävendahl L, Oostra BA, van Duijn C, Hofman A, Rivadeneira F, Uitterlinden AG, Drop SL, Kayser M. Common DNA variants predict tall stature in Europeans. Human genetics 2014 133:5 587-97 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1007/s00439-013-1394-0
54	Zaman F, Chrysis D, Huntjens K, Chagin A, Takigawa M, Fadeel B, Sävendahl L. Dexamethasone differentially regulates Bcl-2 family proteins in human proliferative chondrocytes: role of pro-apoptotic Bid. Toxicology letters 2014 224:2 196-200 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/j.toxlet.2013.10.020
55	Dasgupta D, Wee MJ, Reyes M, Li Y, Simm PJ, Sharma A, Schlingmann KP, Janner M, Biggin A, Lazier J, Gessner M, Chrysis D, Tuchman S, Baluarte HJ, Levine MA, Tiosano D, Insogna K, Hanley DA, Carpenter TO, Ichikawa S, Hoppe B, Konrad M, Sävendahl L, Munns CF, Lee H, Jüppner H, Bergwitz C. Mutations in SLC34A3/NPT2c are associated with kidney stones and nephrocalcinosis. Journal of the American Society of Nephrology : JASN 2014 25:10 2366-75 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1681/ASN.2013101085
56	Movérare-Skrtic S, Henning P, Liu X, Nagano K, Saito H, Börjesson AE, Sjögren K, Windahl SH, Farman H, Kindlund B, Engdahl C, Koskela A, Zhang FP, Eriksson EE, Zaman F, Hammarstedt A, Isaksson H, Bally M, Kassem A, Lindholm C, Sandberg O, Aspenberg P, Sävendahl L, Feng JQ, Tuckermann J, Tuukkanen J, Poutanen M, Baron R, Lerner UH, Gori F, Ohlsson C. Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures. Nature medicine 2014 20:11 1279-88 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/nm.3654
57	Eriksson E, Wickström M, Perup LS, Johnsen JI, Eksborg S, Kogner P, Sävendahl L. Protective role of humanin on bortezomib-induced bone growth impairment in anticancer treatment. Journal of the National Cancer Institute 2014 106:3 djt459- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1093/jnci/djt459
58	Benyi E, Kieler H, Linder M, Ritzén M, Carlstedt-Duke J, Tuvemo T, Westphal O, Sävendahl L. Risks of malignant and non-malignant tumours in tall women treated with high-dose oestrogen during adolescence. Hormone research in paediatrics 2014 82:2 89-96 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000360137
59	Wang L, Benedito R, Bixel MG, Zeuschner D, Stehling M, Sävendahl L, Haigh JJ, Snippert H, Clevers H, Breier G, Kiefer F, Adams RH. Identification of a clonally expanding haematopoietic compartment in bone marrow. The EMBO journal 2013 32:2 219-30 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/emboj.2012.308
60	Karimian E, Tamm C, Chagin AS, Samuelsson K, Kjartansdóttir KR, Ohlsson C, Sävendahl L. Resveratrol treatment delays growth plate fusion and improves bone growth in female rabbits. PloS one 2013 8:6 e67859- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1371/journal.pone.0067859
61	Höybye C, Sävendahl L, Christesen HT, Lee P, Pedersen BT, Schlumpf M, Germak J, Ross J. The NordiNet® International Outcome Study and NovoNet® ANSWER Program®: rationale, design, and methodology of two international pharmacoepidemiological registry-based studies monitoring long-term clinical and safety outcomes of growth hormone therapy (Norditropin®). Clinical epidemiology 2013 5: 119-27 View record in PubMed® Fulltext: https://doi.org/10.2147/CLEP.S42602
62	Bergström I, Blanck A, Sävendahl L. Vitamin D levels in children born to vitamin D-deficient mothers. Hormone research in paediatrics 2013 80:1 6-10 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000351809
63	Zaman F, Chrysis D, Huntjens K, Fadeel B, Savendahl L. Ablation of the Pro-Apoptotic Protein Bax Protects Mice from Glucocorticoid-Induced Bone Growth Impairment. PLOS ONE 2012 7:3 e33168- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1371/journal.pone.0033168
64	Eriksson E, Zaman F, Chrysis D, Wehtje H, Heino TJ, Sävendahl L. Bortezomib is cytotoxic to the human growth plate and permanently impairs bone growth in young mice. PloS one 2012 7:11 e50523- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1371/journal.pone.0050523
65	Lee PA, Sävendahl L, Oliver I, Tauber M, Blankenstein O, Ross J, Snajderova M, Rakov V, Pedersen BT, Christesen HT. Comparison of response to 2-years' growth hormone treatment in children with isolated growth hormone deficiency, born small for gestational age, idiopathic short stature, or multiple pituitary hormone deficiency: combined results from two large observational studies. International journal of pediatric endocrinology 2012 2012:1 22- View record in PubMed® Fulltext: https://doi.org/10.1186/1687-9856-2012-22
66	Savendahl L, Blankenstein O, Oliver I, Christesen HT, Lee P, Pedersen BT, Rakov V, Ross J. Gender Influences Short-Term Growth Hormone Treatment Response in Children. HORMONE RESEARCH IN PAEDIATRICS 2012 77:3 188-94 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000337570
67	Savendahl L, Maes M, Albertsson-Wikland K, Borgstrom B, Carel JC, Henrard S, Speybroeck N, Thomas M, Zandwijken G, Hokken-Koelega A. Long-Term Mortality and Causes of Death in Isolated GHD, ISS, and SGA Patients Treated with Recombinant Growth Hormone during Childhood in Belgium, The Netherlands, and Sweden: Preliminary Report of 3 Countries Participating in the EU SAGhE Study. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2012 97:2 E213-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jc.2011-2882
68	Fernandez-Vojvodich P, Palmblad K, Karimian E, Andersson U, Savendahl L. Pro-Inflammatory Cytokines Produced by Growth Plate Chondrocytes May Act Locally to Modulate Longitudinal Bone Growth. HORMONE RESEARCH IN PAEDIATRICS 2012 77:3 180-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000337569
69	Sävendahl L. The effect of acute and chronic stress on growth. Science signaling 2012 5:247 pt9- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1126/scisignal.2003484
70	Borjesson AE, Windahl SH, Karimian E, Eriksson EE, Lagerquist MK, Engdahl C, Antal MC, Krust A, Chambon P, Savendahl L, Ohlsson C. The role of estrogen receptor-α and its activation function-1 for growth plate closure in female mice. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 2012 302:11 E1381-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1152/ajpendo.00646.2011
71	Karimian E, Chagin AS, Sävendahl L. Genetic regulation of the growth plate. Frontiers in endocrinology 2011 2: 113- View record in PubMed® Fulltext: https://doi.org/10.3389/fendo.2011.00113
72	Chrysis D, Chagin AS, Savendahl L. Insulin-like growth factor-1 restores dexamethasone-induced heart growth arrest in rats: the role of the ubiquitin pathway. HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM 2011 10:1 46-56 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.14310/horm.2002.1292
73	Heino TJ, Astrom E, Laurencikas E, Savendahl L, Soderhall S. Intravenous Pamidronate Treatment Improves Growth in Prepubertal Osteogenesis Imperfecta Patients. HORMONE RESEARCH IN PAEDIATRICS 2011 75:5 354-61 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000323370
74	Fernandez-Vojvodich P, Karimian E, Savendahl L. The Biologics Anakinra and Etanercept Prevent Cytokine-Induced Growth Retardation in Cultured Fetal Rat Metatarsal Bones. HORMONE RESEARCH IN PAEDIATRICS 2011 76:4 278-85 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000330726
75	Chagin AS, Karimian E, Sundstrom K, Eriksson E, Savendahl L. Catch-up growth after dexamethasone withdrawal occurs in cultured postnatal rat metatarsal bones. JOURNAL OF ENDOCRINOLOGY 2010 204:1 21-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1677/JOE-09-0307
76	Benyi E, Berner M, Bjernekull I, Boman A, Chrysis D, Nilsson O, Waehre A, Wehtje H, Sävendahl L. Efficacy and Safety of Percutaneous Epiphysiodesis Operation around the Knee to Reduce Adult Height in Extremely Tall Adolescent Girls and Boys. International journal of pediatric endocrinology 2010 2010: 740629- View record in PubMed® Fulltext: https://doi.org/10.1155/2010/740629
77	Emons J, Chagin AS, Malmlof T, Lekman M, Tivesten A, Ohlsson C, Wit JM, Karperien M, Savendahl L. Expression of vascular endothelial growth factor in the growth plate is stimulated by estradiol and increases during pubertal development. JOURNAL OF ENDOCRINOLOGY 2010 205:1 61-8 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1677/JOE-09-0337
78	Lindahl E, Nyman U, Zaman F, Palmberg C, Cascante A, Shafqat J, Takigawa M, Savendahl L, Jorvall H, Joseph B. Proinsulin C-peptide Regulates Ribosomal RNA Expression. JOURNAL OF BIOLOGICAL CHEMISTRY 2010 285:5 3462-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1074/jbc.M109.053587
79	Borjesson AE, Lagerquist MK, Liu C, Shao RJ, Windahl SH, Karlsson C, Sjogren K, Moverare-Skrtic S, Antal MC, Krust A, Mohan S, Chambon P, Savendahl L, Ohlsson C. The Role of Estrogen Receptor α in Growth Plate Cartilage for Longitudinal Bone Growth. JOURNAL OF BONE AND MINERAL RESEARCH 2010 25:12 2690-700 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1002/jbmr.156
80	Thodberg HH, Savendahl L. Validation and Reference Values of Automated Bone Age Determination for Four Ethnicities. ACADEMIC RADIOLOGY 2010 17:11 1425-32 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/j.acra.2010.06.007
81	Chagin AS, Vannesjo J, Savendahl L. Androgen Receptor Modulation Does Not Affect Longitudinal Growth of Cultured Fetal Rat Metatarsal Bones. HORMONE RESEARCH 2009 71:4 219-27 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000201111
82	Emons J, Chagin AS, Hultenby K, Zhivotovsky B, Wit JM, Karperien M, Savendahl L. Epiphyseal Fusion in the Human Growth Plate Does not Involve Classical Apoptosis. PEDIATRIC RESEARCH 2009 66:6 654-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1203/PDR.0b013e3181beaa8c
83	Chagin AS, Savendahl L. Genes of Importance in the Hormonal Regulation of Growth Plate Cartilage. HORMONE RESEARCH 2009 71: 41-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000192435
84	Ahmed SF, Savendahl L. Promoting Growth in Chronic Inflammatory Disease: Lessons from Studies of the Growth Plate. HORMONE RESEARCH 2009 72: 42-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000229763
85	Windahl SH, Andersson N, Chagin AS, Martensson UEA, Carlsten H, Olde B, Swanson C, Moverare-Skrtic S, Savendahl L, Lagerquist MK, Leeb-Lundberg LMF, Ohlsson C. The role of the G protein-coupled receptor GPR30 in the effects of estrogen in ovariectomized mice. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 2009 296:3 E490-6 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1152/ajpendo.90691.2008
86	Heino TJ, Chagin AS, Takigawa M, Savendahl L. Effects of alendronate and pamidronate on cultured rat metatarsal bones: Failure to prevent dexamethasone-induced growth retardation. BONE 2008 42:4 702-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/j.bone.2008.01.001
87	Rafael E, Tibell A, Rydén M, Lundgren T, Sävendahl L, Borgström B, Arnelo U, Isaksson B, Nilsson B, Korsgren O, Permert J. Intramuscular autotransplantation of pancreatic islets in a 7-year-old child: a 2-year follow-up. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008 8:2 458-62 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/j.1600-6143.2007.02060.x
88	Karimian E, Chagin AS, Gjerde J, Heino T, Lien EA, Ohllsson C, Savendahl L. Tamoxifen impairs both longitudinal and cortical bone growth in young male rats. JOURNAL OF BONE AND MINERAL RESEARCH 2008 23:8 1267-77 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1359/jbmr.080319
89	Miclea RL, Phillip M, Sävendahl L, Wit JM. The 7th ESPE Growth Plate Working Group symposium--EUROGROP, June 27th 2007, Helsinki, Finland. Journal of pediatric endocrinology & metabolism : JPEM 2008 21:3 287-94 View record in PubMed® Fulltext: https://doi.org/10.1515/jpem.2008.21.3.287
90	Heino TJ, Chagin AS, Savendahl L. The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone. JOURNAL OF ENDOCRINOLOGY 2008 197:2 R1-6 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1677/JOE-07-0629
91	Vojvodich PF, Hansen JB, Andersson U, Savendahl L, Hagelberg S. Etanercept treatment improves longitudinal growth in prepubertal children with juvenile idiopathic arthritis. JOURNAL OF RHEUMATOLOGY 2007 34:12 2481-5 View record in PubMed® View record in Web of Science®
92	Chagin AS, Savendahl L. GPR30 estrogen receptor expression in the growth plate declines as puberty progresses. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2007 92:12 4873-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jc.2007-0814
93	Zaman F, Menendez-Benito V, Eriksson E, Chagin AS, Takigawa M, Fadeel B, Dantuma NP, Chrysis D, Saevendahl L. Proteasome inhibition up-regulates p53 and apoptosis-inducing factor in chondrocytes causing severe growth retardation in mice. CANCER RESEARCH 2007 67:20 10078-86 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1158/0008-5472.CAN-06-3982
94	Chagin AS, Karimian E, Zaman F, Takigawa M, Chrysis D, Savendahl L. Tamoxifen induces permanent growth arrest through selective induction of apoptosis in growth plate chondrocytes in cultured rat metatarsal bones. BONE 2007 40:5 1415-24 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/j.bone.2006.12.066
95	Chagin AS, Chrysis D, Takigawa M, Ritzen EM, Savendahl L. Locally produced estrogen promotes fetal rat metatarsal bone growth; an effect mediated through increased chondrocyte proliferation and decreased apoptosis. JOURNAL OF ENDOCRINOLOGY 2006 188:2 193-203 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1677/joe.1.06364
96	Laurencikas E, Savendahl L, Jorulf H. Metacarpophalangeal pattern profile analysis: Useful diagnostic tool for differentiating between dyschondrosteosis, Turner syndrome, and hypochondroplasia. ACTA RADIOLOGICA 2006 47:5 518-24 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1080/02841850600635939
97	Kalirai H, Phillip M, Savendahl L, Wit JM. The Fifth European Growth Plate Working Group Symposium - 21st September 2005, Lyon, France - Abstracts. JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM 2006 19:2 183-90 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1515/jpem.2006.19.2.183
98	Chrysis D, Zaman F, Chagin AS, Takigawa M, Savendahl L. Dexamethasone induces apoptosis in proliferative chondrocytes through activation of caspases and suppression of the Akt-phosphatidylinositol 3 '-kinase signaling pathway. ENDOCRINOLOGY 2005 146:3 1391-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/en.2004-1152
99	Kugelberg M, Shafiei K, Ohlsson C, Savendahl L, Zetterstrom C. Glucocorticoid eye drops inhibit growth in the newborn rabbit. ACTA PAEDIATRICA 2005 94:8 1096-101 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/j.1651-2227.2005.tb02051.x
100	Savendahl L. Hormonal regulation of growth plate cartilage. HORMONE RESEARCH 2005 64: 94-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000087764
101	Laurencikas E, Soderman E, Davenport M, Jorulf H, Savendahl L. Metacarpophalangeal pattern profile analysis as a tool for early diagnosis of Turner syndrome. ACTA RADIOLOGICA 2005 46:4 424-30 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1080/02841850510020905
102	Kugelberg M, Ohlsson C, Savendahl L. Reduced bone mineral density and radial bone growth in young rabbits treated with dexamethasone eye drops. HORMONE RESEARCH 2005 63:4 165-70 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000084684
103	Tivesten A, Moverare-Skrtic S, Chagin A, Venken K, Salmon P, Vanderschueren D, Savendahl L, Holmang A, Ohlsson C. Additive protective effects of estrogen and androgen treatment on trabecular bone in ovariectomized rats. JOURNAL OF BONE AND MINERAL RESEARCH 2004 19:11 1833-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1359/JBMR.040819
104	Chagin AS, Lindberg MK, Andersson N, Moverare S, Gustafsson JA, Savendahl L, Ohlsson C. Estrogen receptor-beta inhibits skeletal growth and has the capacity to mediate growth plate fusion in female mice. JOURNAL OF BONE AND MINERAL RESEARCH 2004 19:1 72-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1359/JBMR.0301203
105	Martensson K, Chrysis D, Savendahl L. Interleukin-1 beta and TNF-alpha act in synergy to inhibit longitudinal growth in fetal rat metatarsal bones. JOURNAL OF BONE AND MINERAL RESEARCH 2004 19:11 1805-12 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1359/JBMR.040805
106	Chrysis D, Ritzen EM, Savendahl L. Growth retardation induced by dexamethasone is associated with increased apoptosis of the growth plate chondrocytes. JOURNAL OF ENDOCRINOLOGY 2003 176:3 331-7 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1677/joe.0.1760331
107	Nilsson O, Chrysis D, Pajulo I, Boman A, Holst M, Rubinstein J, Ritzen EM, Savendahl L. Localization of estrogen receptors-alpha and -beta and androgen receptor in the human growth plate at different pubertal stages. JOURNAL OF ENDOCRINOLOGY 2003 177:2 319-26 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1677/joe.0.1770319
108	Nilsson O, Falk J, Ritzen EM, Baron J, Savendahl L. Raloxifene acts as an estrogen agonist on the rabbit growth plate. ENDOCRINOLOGY 2003 144:4 1481-5 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/en.2002-221108
109	Chrysis D, Nilsson O, Ritzen EM, Savendahl L. Apoptosis is developmentally regulated in rat growth plate. ENDOCRINE 2002 18:3 271-8 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1385/ENDO:18:3:271
110	Nilsson O, Abad V, Chrysis D, Ritzen EM, Savendahl L, Baron J. Estrogen receptor-alpha and -beta are expressed throughout postnatal development in the rat and rabbit growth plate. JOURNAL OF ENDOCRINOLOGY 2002 173:3 407-14 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1677/joe.0.1730407
111	Kindblom JM, Nilsson O, Hurme T, Ohlsson C, Savendahl L. Expression and localization of Indian hedgehog (Ihh) and parathyroid hormone related protein (PTHrP) in the human growth plate during pubertal development. JOURNAL OF ENDOCRINOLOGY 2002 174:2 R1-6 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1677/joe.0.174r001
112	Davenport ML, Punyasavatsut N, Stewart PW, Gunther DF, Savendahl L, Sybert VP. Growth failure in early life: An important manifestation of Turner syndrome. HORMONE RESEARCH 2002 57:5-6 157-64 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000058376
113	Sjogren K, Hellberg N, Bohlooly-Y M, Savendahl L, Johansson MS, Berglindh T, Bosaeus I, Ohlsson C. Body fat content can be predicted in vivo in mice using a modified dual-energy X-ray absorptiometry technique. JOURNAL OF NUTRITION 2001 131:11 2963-6 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1093/jn/131.11.2963
114	Savendahl L, Davenport ML. Delayed diagnoses of Turner's syndrome: Proposed guidelines for change. JOURNAL OF PEDIATRICS 2000 137:4 455-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1067/mpd.2000.107390
115	Ritzen EM, Nilsson O, Grigelioniene G, Holst M, Savendahl L, Wroblewski J. Estrogens and human growth. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 2000 74:5 383-6 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/s0960-0760(00)00116-3
116	Nilsson LO, Boman A, Savendahl L, Grigelioniene G, Ohlsson C, Ritzen EM, Wroblewski J. Demonstration of estrogen receptor-beta immunoreactivity in human growth plate cartilage. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 1999 84:1 370-3 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jcem.84.1.5531
117	Vidal O, Lindberg M, Savendahl L, Lubahn DB, Ritzen EM, Gustafsson JA, Ohlsson C. Disproportional body growth in female estrogen receptor-alpha-inactivated mice. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 1999 265:2 569-71 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1006/bbrc.1999.1711
118	Savendahl L, Underwood LE. Fasting increases serum total cholesterol, LDL cholesterol and apolipoprotein B in healthy, nonobese humans. JOURNAL OF NUTRITION 1999 129:11 2005-8 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1093/jn/129.11.2005
119	Davenport ML, Punyasavatsut N, Gunther D, Savendahl L, Stewart PW. Turner syndrome: a pattern of early growth failure. ACTA PAEDIATRICA 1999 88: 118-21 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/j.1651-2227.1999.tb14419.x
120	Savendahl L, Underwood LE. Decreased interleukin-2 production from cultured peripheral blood mononuclear cells in human acute starvation. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 1997 82:4 1177-80 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/jcem.82.4.3865
121	Savendahl L, Underwood LE, Haldeman KM, Ulshen MH, Lund PK. Fasting prevents experimental murine colitis produced by dextran sulfate sodium and decreases interleukin-1 beta and insulin-like growth factor I messenger ribonucleic acid. ENDOCRINOLOGY 1997 138:2 734-40 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/endo.138.2.4941
122	Savendahl L, Mar MH, Underwood LE, Zeisel SH. Prolonged fasting in humans results in diminished plasma choline concentrations but does not cause liver dysfunction. AMERICAN JOURNAL OF CLINICAL NUTRITION 1997 66:3 622-5 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1093/ajcn/66.3.622
123	Lindstrom P, Savendahl L. Enrichment of type I and type II rat somatotrophs: Characterization of growth hormone secretion in vitro. ENDOCRINOLOGY 1996 137:10 4174-80 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/endo.137.10.8828474
124	ENGSTROM KG, SAVENDAHL L. CELL-VOLUME AND SHAPE OSCILLATIONS IN RAT TYPE-II SOMATOTROPHS AT HYPOTONIC CONDITIONS. CYTOMETRY 1995 20:1 7-13 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1002/cyto.990200103
125	SAVENDAHL LSG, GRANKVIST K, ENGSTROM KG. GROWTH-HORMONE DEFICIENCY IMPAIRS BLOOD-CLOTTING AND REDUCES FACTOR-VII COAGULANT ACTIVITY IN RAT. THROMBOSIS AND HAEMOSTASIS 1995 73:4 626-9 View record in PubMed® View record in Web of Science®

Review

1	Velentza L, Zaman F, Sävendahl L. Bone health in glucocorticoid-treated childhood acute lymphoblastic leukemia. Critical reviews in oncology/hematology 2021 168: 103492- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/j.critrevonc.2021.103492
2	Wood CL, Soucek O, Wong SC, Zaman F, Farquharson C, Savendahl L, Ahmed SF. Animal models to explore the effects of glucocorticoids on skeletal growth and structure. The Journal of endocrinology 2018 236:1 R69-R91 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/JOE-17-0361
3	Benyi E, Sävendahl L. The Physiology of Childhood Growth: Hormonal Regulation. Hormone research in paediatrics 2017 88:1 6-14 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000471876
4	Hokken-Koelega A, van der Lely AJ, Hauffa B, Häusler G, Johannsson G, Maghnie M, Argente J, DeSchepper J, Gleeson H, Gregory JW, Höybye C, Keleştimur F, Luger A, Müller HL, Neggers S, Popovic-Brkic V, Porcu E, Sävendahl L, Shalet S, Spiliotis B, Tauber M. Bridging the gap: metabolic and endocrine care of patients during transition. Endocrine connections 2016 5:6 R44-R54 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/EC-16-0028
5	Baron J, Sävendahl L, De Luca F, Dauber A, Phillip M, Wit JM, Nilsson O. Short and tall stature: a new paradigm emerges. Nature reviews. Endocrinology 2015 11:12 735-46 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/nrendo.2015.165
6	Sederquist B, Fernandez-Vojvodich P, Zaman F, Sävendahl L. Recent research on the growth plate: Impact of inflammatory cytokines on longitudinal bone growth. Journal of molecular endocrinology 2014 53:1 T35-44 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/JME-14-0006
7	Karimian E, Sävendahl L. Estrogen signaling in growth plate cartilage. Endocrine development 2011 21: 42-51 View record in PubMed® Fulltext: https://doi.org/10.1159/000328126
8	Cassorla F, Cianfarani S, Haverkamp F, Labarta JI, Loche S, Luo X, Maghnie M, Mericq V, Muzsnai A, Norgren S, Ojaniemi M, Pribilincova Z, Quinteiro S, Savendahl L, Spinola e Castro A, Gasteyger C. Growth hormone and treatment outcomes: expert review of current clinical practice. Pediatric endocrinology reviews : PER 2011 9:2 554-65 View record in PubMed®
9	Emons J, Chagin AS, Savendahl L, Karperien M, Wit JM. Mechanisms of Growth Plate Maturation and Epiphyseal Fusion. HORMONE RESEARCH IN PAEDIATRICS 2011 75:6 383-91 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000327788
10	Martin DD, Wit JM, Hochberg Z, Savendahl L, van Rijn RR, Fricke O, Cameron N, Caliebe J, Hertel T, Kiepe D, Albertsson-Wikland K, Thodberg HH, Binder G, Ranke MB. The Use of Bone Age in Clinical Practice - Part 1. HORMONE RESEARCH IN PAEDIATRICS 2011 76:1 1-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000329372
11	Andrade AC, Baron J, Manolagas SC, Shaw NJ, Rappold GA, Donaldson MDC, Gault EJ, Savendahl L. Hormones and Genes of Importance in Bone Physiology and Their Influence on Bone Mineralization and Growth in Turner Syndrome. HORMONE RESEARCH IN PAEDIATRICS 2010 73:3 161-5 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1159/000284356
12	Benjamin RW, Moats-Staats BM, Calikoglu's A, Savendahl L, Chrysis D. Hypercalcemia in children. Pediatric endocrinology reviews : PER 2008 5:3 778-84 View record in PubMed®
13	Chagin AS, Sävendahl L. Estrogens and growth: review. Pediatric endocrinology reviews : PER 2007 4:4 329-34 View record in PubMed®
14	Chagin AS, Savendahl L. Oestrogen receptors and linear bone growth. ACTA PAEDIATRICA 2007 96:9 1275-9 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/j.1651-2227.2007.00415.x

Letter

1	Sävendahl L, Battelino T, Brod M, Højby Rasmussen M, Juul Kildemoes R, Saenger P. Letter to the Editor From Sävendahl et al.: "Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial". The Journal of clinical endocrinology and metabolism 2022 107:2 e888-e889 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/clinem/dgab736
2	Tidblad A, Sävendahl L. Growth Hormone Use in Childhood and Adult Cardiovascular Disease-Reply. JAMA pediatrics 2021 175:6 646-647 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1001/jamapediatrics.2021.0241
3	Zaman F, Savendahl L. New Agents to Treat Chronic Lymphocytic Leukemia. The New England journal of medicine 2016 374:22 2185- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1056/NEJMc1602674
4	Zaman F, Kogner P, Savendahl L. Venetoclax in cancer therapy and potential effects on bone. LANCET ONCOLOGY 2016 17:8 e319-e320 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1016/S1470-2045(16)30228-5
5	Eriksson E, Sävendahl L, Zaman F. Bortezomib and bone health in adults: can we extend these findings to children?. European journal of haematology 2013 90:6 533-4 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/ejh.12101
6	Zaman F, Fadeel B, Savendahl L. Proteasome inhibition therapies in childhood cancer. LEUKEMIA 2008 22:4 883-4 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1038/sj.leu.2404997
7	Davenport ML, Savendahl L. Screening for Turner's syndrome by chromosome analysis of all girls with short stature - Reply. JOURNAL OF PEDIATRICS 2002 140:1 140-141 View record in Web of Science® Fulltext: https://doi.org/10.1067/mpd.2002.119171

Editorial

1	Fernandez-Vojvodich P, Zaman F, Sävendahl L. Interleukin-6 acts locally on the growth plate to impair bone growth. Annals of the rheumatic diseases 2013 72:10 e24- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1136/annrheumdis-2013-204112
2	Savendahl L. Vitamin D deficiency during pregnancy-potential threat to the child. ACTA PAEDIATRICA 2011 100:4 484-5 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1111/j.1651-2227.2011.02133.x

Other

1	Robertsson C, Sävendahl L, Cardemil C. Primary chronic osteomyelitis of the jaw: Rapid improvement after hormonal suppression in a girl with precocious puberty. Bone reports 2021 14: 101089- View record in PubMed® Fulltext: https://doi.org/10.1016/j.bonr.2021.101089
2	Savendahl L, Battelino T, Brod M, Rasmussen MH, Horikawa R, Juul RV, Saenger P, REAL 3 Study Grp. Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial (vol 105, pg e1847, 2020). JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2020 105:12 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/clinem/dgaa614
3	Savendahl L, Polak M, Backeljauw P, Blair J, Miller B, Rohrer T, Pietropoli A, Ostrow V, Ross J. Treatment of Children With GH in the United States and Europe: Long-Term Follow-Up From NordiNet (R) IOS and ANSWER Program (vol 104, pg 4730, 2019). JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2020 105:6 View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1210/clinem/dgaa139
4	Sävendahl L, Pournara E, Pedersen BT, Blankenstein O. Is safety of childhood growth hormone therapy related to dose? Data from a large observational study. European journal of endocrinology 2017 176:3 X1- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1530/EJE-15-1017e
5	Lindahl E, Nyman U, Zaman F, Palmberg C, Cascante A, Shafqat J, Takigawa M, Sävendahl L, Jörnvall H, Joseph B. Proinsulin C-peptide regulates ribosomal RNA expression. The Journal of biological chemistry 2017 292:10 4382- View record in PubMed® View record in Web of Science® Fulltext: https://doi.org/10.1074/jbc.A109.053587
6	Späth SS, Sävendahl L, Camacho-Hübner C, Nilsson O. Highlights from the Second European Workshop on Growth Plate Research 2010. Pediatric endocrinology reviews : PER 2010 8:2 123-5 View record in PubMed®
7	Ross J, Savendahl L, Gruters A, Oliver I, Peterkova V, Snajderova M, Germak J, Pedersen BT, Rakov V. Gender differences in growth hormone (GH) responsiveness in growth hormone deficient (GHD) children and short children born small for gestational age (SGA). HORMONE RESEARCH 2009 72: 372-372 View record in Web of Science®
8	Savendahl L, Ross J, Fujieda K, Tajima T, Gruters A, Blankenstein O, Oliver I, Pienkowski C, Snajderova M, Peterkova V, Pedersen BT, Germak J, Rakov V. Gender disproportion in children treated with growth hormone depends on country/region, diagnosis and severity of growth retardation. HORMONE RESEARCH 2009 72: 373-373 View record in Web of Science®
9	Emons JAM, Leijten J, van Zwet E, Goeman J, Decker E, Chagin A, Sticht C, Yu XL, van Gool SA, Pirzer H, Rappold GA, Gretz N, Wit JM, Savendahl L, Karperien M. Genome wide screening and morphological analysis of the human growth plate during pubertal development. HORMONE RESEARCH 2009 72: 275-276 View record in Web of Science®
10	Heino TJ, Astrom E, Savendahl L, Soderhall S. Improved growth during the first year of monthly intravenous pamidronate therapy in prepubertal patients with osteogenesis imperfecta. HORMONE RESEARCH 2009 72: 223-223 View record in Web of Science®
11	Ross J, Savendahl L, Karwe V, Germak J, Rakov V. Predictors of growth response after one year of Norditropin (R) treatment in Turner syndrome patients from the ANSWER program (R) and the NordiNet (R). HORMONE RESEARCH 2009 72: 372-373 View record in Web of Science®
12	Ross J, Savendahl L, Karwe V, Rakov V, Germak J. Predictors of growth response after one year of Norditropin treatment in growth hormone deficient (GHD) patients from the ANSWER program (R) and NordiNet (R). HORMONE RESEARCH 2009 72: 372-372 View record in Web of Science®
13	Karimian E, Savendahl L. Resveratrol modulates longitudinal bone growth of cultured fetal rat metatarsal bones in a biphasic manner. HORMONE RESEARCH 2009 72: 277-278 View record in Web of Science®
14	Eriksson E, Johnsen JI, Kogner P, Savendahl L. The proteasome inhibitor, bortezomib induces growth retardation and delays tumor growth in young mice. HORMONE RESEARCH 2009 72: 276-276 View record in Web of Science®
15	Zaman F, Chrysis D, Huntjens K, Takigawa M, Fadeel B, Savendahl L. Dexamethasone Triggers Mitochondrial Apoptosis Through Bax in Proliferative Growth Plate Chondrocytes Causing Growth Retardation. JOURNAL OF BONE AND MINERAL RESEARCH 2008 23: S53-S53 View record in Web of Science®
16	Berner M, Wehtje H, Savendahl L. Efficacy and safety of bilateral epiphysiodesis performed in extremely tall girls and boys. HORMONE RESEARCH 2008 70: 113-113 View record in Web of Science®
17	Emons J, Chagin AS, Hultenby K, Zhivotovsky B, Wit JM, Karperien M, Savendahl L. Epiphyseal fusion in the human growth plate does not involve classical apoptosis. HORMONE RESEARCH 2008 70: 37-37 View record in Web of Science®
18	Heino TJ, Chagin AS, Savendahl L. GPR30 estrogen receptor expression in bone cells during pubertal development. CALCIFIED TISSUE INTERNATIONAL 2008 82: S155-S155 View record in Web of Science®
19	Karperien M, Emons J, van Gool S, Chagin A, Savendahl L, Rappold G, Wit JM. Molecular regulation of the growth plate: Genome-wide expression analysis of human growth plate chondrocytes. An ESPE-RU update. HORMONE RESEARCH 2008 70: 9-9 View record in Web of Science®
20	Eriksson E, Zaman F, Ysis DC, Savendahl L. Proteasome inhibition causes permanent growth retardation in young mice. HORMONE RESEARCH 2008 70: 37-38 View record in Web of Science®
21	Windahl SH, Andersson N, Chagin A, Martensson UE, Carlsten H, Olde B, Leeb-Lundberg LMF, Swanson C, Savendahl L, Lagerquist MK, Ohlsson C. The Role of the G Protein-coupled Receptor GPR30 in Effects of Estrogen in Ovariectomized Mice.. JOURNAL OF BONE AND MINERAL RESEARCH 2008 23: S284-S284 View record in Web of Science®
22	Sundstrom K, Chagin AS, Camacho-Hubner C, Savendahl L. Time-dependent growth responsiveness to rhIGF-I in cultured rat metatarsal bones. HORMONE RESEARCH 2008 70: 19-19 View record in Web of Science®
23	Thodberg HH, Savendahl L. Validation of authomated bone age determination in healthy American children of four ethnicities. HORMONE RESEARCH 2008 70: 88-88 View record in Web of Science®
24	Heino TJ, Chagin AS, Savendahl L. Bisphosphonates stimulate linear growth of fetal rat metatarsal bones and protect chondrocytes from dexamethasone-induced apoptosis. CALCIFIED TISSUE INTERNATIONAL 2007 80: S130-S130 View record in Web of Science®
25	Miclea RL, Phillip M, Sävendahl L, Wit JM. Meeting Report:The 7th ESPE Growth Plate Working Group Symposium - EUROGROP June 27th 2007, Helsinki, Finland. Pediatric endocrinology reviews : PER 2007 5:2 680-5 View record in PubMed®
26	Thodberg HH, Savendahl L. Accuracy of a new automatic method to determine Greulich-Pyle bone age. HORMONE RESEARCH 2006 65: 21-21 View record in Web of Science®
27	Karimian E, Vojvodich PF, Savendahl L. Biologic response modifiers completely rescue cytokine-induced growth retardation in fetal rat metatarsal bones. HORMONE RESEARCH 2006 65: 28-28 View record in Web of Science®
28	Savendahl L. Cytokines and their effect on growth plate chondrocytes. HORMONE RESEARCH 2006 65: 7-8 View record in Web of Science®
29	Malmlof T, Chagin A, Tivesten A, Savendahl L. Estrogen induced VEGF-expression in the rat growth plate. HORMONE RESEARCH 2006 65: 27-28 View record in Web of Science®
30	Eriksson E, Zaman F, Chrysis D, Savendahl L. Proteasome inhibitors induce growth retardation in mice and apoptosis in growth plate chondrocytes. HORMONE RESEARCH 2006 65: 20-20 View record in Web of Science®
31	Chagin A, Nilsson M, Wright KD, Savendahl L. Remaining estrogenic activity in the man with mutated estrogen receptor alpha [ER alpha). HORMONE RESEARCH 2006 65: 28-28 View record in Web of Science®
32	Emons J, Phillip M, Wit JM, Sävendahl L. The Sixth ESPE Growth Plate Working Group Symposium (EUROGROP), June 30th, Rotterdam, the Netherlands, "a multidisciplinary approach to growth plate biology". Pediatric endocrinology reviews : PER 2006 4:2 153-9 View record in PubMed®
33	Chagin A, Phillip M, Wit JM, Sävendahl L. The 4th European Growth Plate Working Group Symposium (EUROGROP). 10th September 2004, Basel, Switzerland. Journal of pediatric endocrinology & metabolism : JPEM 2005 18:8 823-7 View record in PubMed®
34	Moverare S, Tivesten A, Chagin A, Venken K, Salmon P, Vanderschueren D, Savendahl L, Holmang A, Ohlsson C. Additive stimulatory effects of estrogen and androgen receptor activation on trabecular bone in ovariectomized rats.. JOURNAL OF BONE AND MINERAL RESEARCH 2004 19: S170-S170 View record in Web of Science®
35	Robson H, Savendahl L, Phillip M, Wit JM. The Third European Growth Plate Working Group Symposium. 17th September 2003, Ljubljana, Slovenia. Journal of pediatric endocrinology & metabolism : JPEM 2004 17:4 685-94 View record in PubMed® Fulltext: https://doi.org/10.1515/jpem.2004.17.4.685
36	Nilsson O, Falk J, Ritzen ME, Baron J, Savendahl L. Raloxifene acts as an estrogen agonist on the rabbit growth plate. PEDIATRIC RESEARCH 2003 53:4 151A-152A View record in Web of Science®
37	Nilsson O, Abad V, Savendahl LSG, Baron J. Expression of estrogen receptor-beta in rabbit growth plate cartilage.. JOURNAL OF BONE AND MINERAL RESEARCH 1999 14: S452-S452 View record in Web of Science®